Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EPOR | P19235 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 10/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | MMP14 | P50281 | 6/20 | 0.37 |
| ▸ | MMP9 | P14780 | 5/20 | 0.37 |
| ▸ | MMP13 | P45452 | 5/20 | 0.37 |
| ▸ | MMP3 | P08254 | 4/20 | 0.37 |
| ▸ | MMP1 | P03956 | 4/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 4/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP16 | P51512 | 2/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4292057 | 0.92 | TBXA2R (0.38) | LMNAMMP2MMP14MMP9NR3C1 | |
| SCHEMBL4380644 | 0.81 | MMP2 (0.43) | EPORMMP2CA1CA2CA9 | |
| SCHEMBL1799173 | 0.79 | MMP2 (0.41) | LMNAHTTMMP2CA1CA2 | |
| SCHEMBL1801225 | 0.78 | BMP1 (0.51) | MMP2MMP14MMP9MMP13MMP3 | |
| SCHEMBL1800017 | 0.77 | MMP2 (0.44) | LMNAHTTEPORMMP2MMP14 | |
| SCHEMBL4382917 | 0.76 | MMP2 (0.40) | LMNAHTTEPORMMP2MMP14 | |
| SCHEMBL4299320 | 0.74 | KMT2A (0.39) | LMNAMMP2CA9CA12MMP9 | |
| SCHEMBL4374166 | 0.72 | MMP2 (0.45) | MMP2MMP14MMP9MMP13MMP3 | |
| SCHEMBL4288106 | 0.72 | MMP3 (0.41) | LMNAHTTMMP2MMP14MMP9 | |
| SCHEMBL4288103 | 0.72 | MMP3 (0.41) | LMNAHTTMMP2MMP14MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247451-B2 | ADAM10 and its uses related to infection | VANDERBILT UNIVERSITY (US) | 2012-08-21 | — | — | US | disclosed |
| US-20090220514-A1 | ADAM10 and its Uses Related to Infection | VANDERBILT UNIVERSITY | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090220514-A1 | ADAM10 and its Uses Related to Infection | ADAM10, ADAM12, ADAM17 | LMNA 1700/4885HTT 4332/4885EPOR 4688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.