Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753413 | 0.77 | TDP1 (0.51) | FKBP1ALMNAHPGDNPC1RAB9A | |
| SCHEMBL4751878 | 0.77 | CYP1A2 (0.49) | ALDH1A1HPGDDRD2DRD3MEN1 | |
| SCHEMBL4753498 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EDRD3NPC1MEN1 | |
| SCHEMBL7345420 | 0.75 | LMNA (0.50) | LMNAALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL6964456 | 0.75 | LMNA (0.50) | LMNAALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL12342032 | 0.74 | KMT2A (0.49) | LMNAALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL12341996 | 0.74 | LMNA (0.52) | LMNAALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL11692415 | 0.73 | ALDH1A1 (0.63) | FKBP1ALMNAALDH1A1HPGDMGLL | |
| SCHEMBL4750352 | 0.73 | RAB9A (0.55) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL4750109 | 0.73 | ALDH1A1 (0.40) | LMNAALDH1A1KDM4EHPGDMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | FKBP1A 1906/4885LMNA 1785/4885CHRM2 3686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.