Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751878 | 0.83 | CYP1A2 (0.49) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1527719 | 0.80 | NR1H4 (0.47) | RAB9ASMN1; SMN2HTTNPC1MAPT | |
| SCHEMBL4299441 | 0.78 | MGLL (0.47) | SMN1; SMN2ALDH1A1HRH2HRH1CYP2C19 | |
| SCHEMBL4753413 | 0.78 | TDP1 (0.51) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL8894258 | 0.76 | NR1H4 (0.44) | RAB9ASMN1; SMN2HTTNPC1MAPT | |
| SCHEMBL4753498 | 0.75 | ALDH1A1 (0.48) | SMN1; SMN2NPC1MAPTMEN1KMT2A | |
| SCHEMBL4750109 | 0.73 | ALDH1A1 (0.40) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4293429 | 0.73 | FKBP1A (0.48) | RAB9AHTTNPC1MAPTMEN1 | |
| SCHEMBL5278939 | 0.72 | NR1H4 (0.52) | RAB9ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL14227022 | 0.71 | MAPT (0.45) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |