SCHEMBL4295716

SCHEMBL4295716

S=C(SSC(=S)n1cccc1)n1cccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 4/20 1.00
MGLL Q99685 5/20 0.33
KDM4A O75164 1/20 0.33
PHGDH O43175 3/20 0.32
ALDH1A1 P00352 1/20 0.32
ALDH2 P05091 1/20 0.32
PDK1 Q15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22182758 0.79
SCHEMBL19257802 0.73 FBP1 (0.56) FBP1
SCHEMBL14142802 0.71 FBP1 (0.54) FBP1
SCHEMBL5278270 0.69 FBP1 (0.53) FBP1
SCHEMBL22088556 0.67
SCHEMBL28258663 0.67
SCHEMBL14456682 0.66 FBP1 (0.48) FBP1
SCHEMBL14130475 0.66 FBP1 (0.48) FBP1
SCHEMBL162985 0.65 FBP1 (0.46) FBP1
SCHEMBL162319 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10954325-B2 Raft agents and their use in the development of polyvinylpyrrolidone grafted nanoparticles UNIVERSITY OF SOUTH CAROLINA (US) 2021-03-23 US disclosed
US-20170298158-A1 NOVEL RAFT AGENTS AND THEIR USE IN THE DEVELOPMENT OF POLYVINYLPYRROLIDONE GRAFTED NANOPARTICLES UNIVERSITY OF SOUTH CAROLINA 2017-10-19 US disclosed
US-20170298158-A1 NOVEL RAFT AGENTS AND THEIR USE IN THE DEVELOPMENT OF POLYVINYLPYRROLIDONE GRAFTED NANOPARTICLES UNIVERSITY OF SOUTH CAROLINA 2017-10-19 US disclosed
US-9732169-B2 Raft agents and their use in the development of polyvinylpyrrolidone grafted nanoparticles UNIVERSITY OF SOUTH CAROLINA (US) 2017-08-15 US disclosed
US-9732169-B2 Raft agents and their use in the development of polyvinylpyrrolidone grafted nanoparticles UNIVERSITY OF SOUTH CAROLINA (US) 2017-08-15 US disclosed
EP-2540734-B1 Process and reagents for oligonucleotide synthesis and purification ALNYLAM PHARMACEUTICALS INC (US) 2016-03-30 EP disclosed
US-20160024234-A1 NOVEL RAFT AGENTS AND THEIR USE IN THE DEVELOPMENT OF POLYVINYLPYRROLIDONE GRAFTED NANOPARTICLES UNIVERSITY OF SOUTH CAROLINA 2016-01-28 US disclosed
US-8431693-B2 Process for desilylation of oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2013-04-30 US disclosed
EP-2540734-A2 Process and reagents for oligonucleotide synthesis and purification Alnylam Pharmaceuticals, Inc. (US) 2013-01-02 EP disclosed
EP-1467966-B1 WATER-SOLUBLE DITHIOESTERS AND METHOD FOR POLYMERIZATION THEREOF LG CHEMICAL LTD (KR) 2012-07-18 EP disclosed
US-20100104974-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2010-04-29 US disclosed
US-20100104974-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2010-04-29 US disclosed
US-20090269683-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND COLOR FILTERS JSR CORPORATION (JP) 2009-10-29 US disclosed
US-20090187027-A1 PROCESSES AND REAGENTS FOR SULFURIZATION OF OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2009-07-23 US disclosed
US-20090187027-A1 PROCESSES AND REAGENTS FOR SULFURIZATION OF OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2009-07-23 US disclosed
US-20090005549-A1 Processes and Reagents for Desilylation of Oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2009-01-01 US disclosed
US-6888020-B2 Water-soluble dithioesters and method for polymerization thereof LG CHEM, LTD. (KR) 2005-05-03 US disclosed
EP-1467966-A2 WATER-SOLUBLE DITHIOESTERS AND METHOD FOR POLYMERIZATION THEREOF LG Chem, Ltd. (KR) 2004-10-20 EP disclosed
US-20040138492-A1 Water-soluble dithioesters and method for polymerization thereof LG CHEM, LTD. (KR) 2004-07-15 US disclosed
WO-2003062280-A2 WATER-SOLUBLE DITHIOESTERS AND METHOD FOR POLYMERIZATION THEREOF LG CHEM, LTD. (KR) 2003-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10954325-B2 Raft agents and their use in the development of polyvinylpyrrolidone grafted nanoparticles ILK, VCL, RFTN1 FBP1 2978/4885MGLL 1535/4885KDM4A 1671/4885
US-20090005549-A1 Processes and Reagents for Desilylation of Oligonucleotides ALKBH1, DIMT1, RNGTT FBP1 1144/4885MGLL 4387/4885KDM4A 1360/4885
US-20160024234-A1 NOVEL RAFT AGENTS AND THEIR USE IN THE DEVELOPMENT OF POLYVINYLPYRROLIDONE GRAFTED NANOPARTICLES ILK, RFTN1, VCL FBP1 2837/4885MGLL 2292/4885KDM4A 1583/4885
US-20170298158-A1 NOVEL RAFT AGENTS AND THEIR USE IN THE DEVELOPMENT OF POLYVINYLPYRROLIDONE GRAFTED NANOPARTICLES ILK, RFTN1, VCL FBP1 2837/4885MGLL 2292/4885KDM4A 1583/4885
US-20040138492-A1 Water-soluble dithioesters and method for polymerization thereof TST, TTPA, TMT1A FBP1 2856/4885MGLL 1428/4885KDM4A 3134/4885
US-20090187027-A1 PROCESSES AND REAGENTS FOR SULFURIZATION OF OLIGONUCLEOTIDES ALKBH1, RNGTT, MTAP FBP1 1146/4885MGLL 4670/4885KDM4A 1772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.