Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21919657 | 0.86 | SIGMAR1 (0.49) | SMN1; SMN2DRD2SIGMAR1ALDH1A1 | |
| SCHEMBL20594570 | 0.86 | SIGMAR1 (0.49) | SMN1; SMN2DRD2SIGMAR1ALDH1A1 | |
| SCHEMBL6964168 | 0.77 | ACHE (0.47) | SLC6A3SIGMAR1ALDH1A1OPRM1OPRD1 | |
| SCHEMBL7441175 | 0.74 | SIGMAR1 (0.66) | MAPTSLC6A3SIGMAR1ACHE | |
| SCHEMBL20523462 | 0.73 | TACR1 (0.50) | SMN1; SMN2DRD2SIGMAR1ALDH1A1 | |
| SCHEMBL28394397 | 0.71 | SLC6A3 (0.59) | GAAHTTMAPTSLC6A3HTR1A | |
| SCHEMBL6056974 | 0.71 | SLC6A3 (0.83) | MAPTSLC6A3HTR1ADRD2SIGMAR1 | |
| SCHEMBL14407778 | 0.71 | SLC6A3 (0.83) | MAPTSLC6A3HTR1ADRD2SIGMAR1 | |
| SCHEMBL13150782 | 0.71 | SLC6A3 (0.83) | MAPTSLC6A3HTR1ADRD2SIGMAR1 | |
| SCHEMBL7264546 | 0.71 | SLC6A3 (0.83) | MAPTSLC6A3HTR1ADRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270379-A1 | QUINOLONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270379-A1 | QUINOLONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | NQO2, QARS1, NQO1 | GAA 480/4885MAPK1 3730/4885HTT 3588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.