Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | CBFB | Q13951 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3728503 | 0.83 | FGFR1 (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL3738781 | 0.81 | SMN1; SMN2 (0.52) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL1051901 | 0.80 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL3731117 | 0.76 | RAB9A (0.62) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL4300429 | 0.75 | CDK1 (0.41) | KDM4EMAPTACHEHPGDFGFR1 | |
| SCHEMBL14795833 | 0.74 | FGFR1 (0.71) | JMJD6MAPTFGFR1FLT1PDGFRB | |
| SCHEMBL1054206 | 0.74 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL3739404 | 0.72 | ADORA3 (0.59) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL13947081 | 0.71 | METAP2 (0.64) | JMJD6NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7281131 | 0.71 | NPBWR1 (0.52) | JMJD6NPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281100-A1 | Benzimidazole quinolinones and uses thereof | BARSANTI PAUL A | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281100-A1 | Benzimidazole quinolinones and uses thereof | GAA, ALPI, IL4I1 | JMJD6 1827/4885NPC1 2233/4885RAB9A 2973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.