Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14993232 | 0.86 | ALDH1A1 (0.33) | ALDH1A1MAPTGAANPSR1ACHE | |
| SCHEMBL4304302 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTGAANPSR1ACHE | |
| SCHEMBL19928616 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPTGAANPSR1ACHE | |
| SCHEMBL13779270 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTGAANPSR1ACHE | |
| SCHEMBL5360647 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTGAANPSR1ACHE | |
| SCHEMBL1634590 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTGAANPSR1ACHE | |
| SCHEMBL13570117 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTGAANPSR1ACHE | |
| SCHEMBL19227398 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTGAANPSR1ACHE | |
| SCHEMBL11794721 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTGAANPSR1ACHE | |
| SCHEMBL7017316 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTGAANPSR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083682-B | A kind of preparation method of the carotenal of β Apos 8 ' | 广州巨元生化有限公司 | 2017-10-27 | — | — | CN | claimed |
| CN-105646311-B | The method that one kind prepares the carrot aldehyde of β Apos 8 ' | 广州巨元生化有限公司 | 2017-09-26 | — | — | CN | claimed |
| CN-106083682-A | A kind of preparation method of β apo-8 ' carotenal | 广州巨元生化有限公司 | 2016-11-09 | — | — | CN | claimed |
| US-11773060-B2 | Method for synthesis of 9-cis-beta-carotene and formulations thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2023-10-03 | — | — | US | disclosed |
| US-20210317143-A9 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-10-14 | — | — | US | disclosed |
| US-20200369685-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2020-11-26 | — | — | US | disclosed |
| WO-2020236253-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-26 | — | — | WO | disclosed |
| EP-2785178-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2019-05-01 | — | — | EP | disclosed |
| US-10201545-B2 | Styrenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC. (US) | 2019-02-12 | — | — | US | disclosed |
| US-10201533-B2 | Substituted quinolizine derivatives useful as HIV integrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2019-02-12 | — | — | US | disclosed |
| US-20190023649-A1 | Opsin-Binding Ligands, Compositions and Methods of Use | BIKAM PHARMACEUTICALS, INC. (US) | 2019-01-24 | — | — | US | disclosed |
| US-8420863-B2 | Styrenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-8420863-B2 | Styrenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-20120129860-A1 | STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2012-05-24 | — | — | US | disclosed |
| US-20120129860-A1 | STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2012-05-24 | — | — | US | disclosed |
| US-20090170841-A1 | Styrenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders | ACUCELA INC. (US) | 2009-07-02 | — | — | US | disclosed |
| US-20090170841-A1 | Styrenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders | ACUCELA INC. (US) | 2009-07-02 | — | — | US | disclosed |
| WO-2008131368-A2 | STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA INC. (US) | 2008-10-30 | — | — | WO | disclosed |
| EP-1961725-A1 | Odorous and aroma substances, their manufacture and utilisation | Symrise GmbH & Co. KG (DE) | 2008-08-27 | — | — | EP | disclosed |
| US-3953524-A | Catalytic hydrogenation of alpha,beta-unsaturated aldehydes to alpha,beta-unsaturated alcohols | HOFFMANN-LA ROCHE INC. (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369685-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | BRCA1, BTD, BCHE | ALDH1A1 731/4885MAPT 1387/4885GAA 32/4885 |
| US-20210317143-A9 | BORONIC ESTER PRODRUGS AND USES THEREOF | BRCA1, BTD, BCHE | ALDH1A1 731/4885MAPT 1387/4885GAA 32/4885 |
| US-20120129860-A1 | STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ALDH1A2, STARD3, TXNRD2 | ALDH1A1 336/4885MAPT 38/4885GAA 1224/4885 |
| US-20190023649-A1 | Opsin-Binding Ligands, Compositions and Methods of Use | CRYAB, CRYAA, PDE6C | ALDH1A1 2346/4885MAPT 1065/4885GAA 2480/4885 |
| US-10201545-B2 | Styrenyl derivative compounds for treating ophthalmic diseases and disorders | ALDH1A2, STARD3, TXNRD2 | ALDH1A1 336/4885MAPT 38/4885GAA 1224/4885 |
| US-20090170841-A1 | Styrenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders | ALDH1A2, STARD3, TXNRD2 | ALDH1A1 336/4885MAPT 38/4885GAA 1224/4885 |
| US-10201533-B2 | Substituted quinolizine derivatives useful as HIV integrase inhibitors | NQO2, CYP3A5, QTRT1 | ALDH1A1 1564/4885MAPT 3742/4885GAA 931/4885 |
| US-11773060-B2 | Method for synthesis of 9-cis-beta-carotene and formulations thereof | BHMT2, CBS, TTPA | ALDH1A1 2244/4885MAPT 3341/4885GAA 3107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.