Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956242 | 0.88 | ALDH1A1 (0.70) | ALDH1A1CYP3A4MAPTKDM4EPOLB | |
| SCHEMBL3320910 | 0.88 | ALDH1A1 (0.70) | ALDH1A1CYP3A4MAPTKDM4EPOLB | |
| SCHEMBL7375373 | 0.80 | GABRP (0.64) | ALDH1A1CYP3A4MAPTKDM4EPOLB | |
| SCHEMBL30269735 | 0.79 | KMT2A (0.68) | ALDH1A1CYP3A4MAPTKDM4EPOLB | |
| SCHEMBL29615754 | 0.79 | KMT2A (0.68) | ALDH1A1CYP3A4MAPTKDM4EPOLB | |
| SCHEMBL10013320 | 0.79 | ABCB1 (0.64) | ALDH1A1CYP3A4MAPTKDM4EPOLB | |
| SCHEMBL28009934 | 0.77 | TERT (0.58) | ALDH1A1CYP3A4MAPTKDM4EPOLB | |
| SCHEMBL22686278 | 0.76 | KDM4E (0.82) | MAPTKDM4EPOLBRECQLAKR1B1 | |
| Gardenin SCHEMBL1764114 | 0.76 | ALDH1A1 (1.00) | ALDH1A1CYP3A4MAPTKDM4EPOLB | |
| SCHEMBL26110312 | 0.75 | ALDH1A1 (0.75) | ALDH1A1CYP3A4MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1493431-B1 | Use of an extract of bauhinia for the preparation of pharmaceutical and cosmetic compositions | MERCK PATENT GMBH (DE) | 2009-09-30 | — | — | EP | disclosed |
| US-20080044502-A1 | USE OF AN AQUEOUS OR HYDROALCOHOLIC EXTRACT OF BAUHINIA FOR THE PREPARATION OF A COMPOSITION | WIRTH CORINNA | 2008-02-21 | — | — | US | disclosed |
| US-20060188591-A1 | Bauhinia extracts | BUCHHOLZ HERWIG | 2006-08-24 | — | — | US | disclosed |
| US-20050019426-A1 | For care, protection from aging of skin and hair, use in treatment of various skin disorders such as leukoplakia, eczema, keratosis, psoriasis, or to promote wound healing | MERCK PATENT GMBH (DE) | 2005-01-27 | — | — | US | disclosed |
| EP-1493431-A2 | Use of an extract of bauhinia for the preparation of pharmaceutical and cosmetic compositions | MERCK PATENT GmbH (DE) | 2005-01-05 | — | — | EP | disclosed |
| EP-1414476-A1 | BAUHINIA EXTRACTS | MERCK PATENT GmbH (DE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011311-A1 | BAUHINIA EXTRACTS | MERCK PATENT GMBH (DE) | 2003-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050019426-A1 | For care, protection from aging of skin and hair, use in treatment of various skin disorders such as leukoplakia, eczema, keratosis, psoriasis, or to promote wound healing | ITCH, CUTA, POLR1C | ALDH1A1 1876/4885CYP3A4 4025/4885MAPT 730/4885 |
| US-20080044502-A1 | USE OF AN AQUEOUS OR HYDROALCOHOLIC EXTRACT OF BAUHINIA FOR THE PREPARATION OF A COMPOSITION | BROX, HAAO, HIRA | ALDH1A1 152/4885CYP3A4 1025/4885MAPT 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.