Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | METAP1 | P53582 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | METAP2 | P50579 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.44 |
| ▸ | CCR8 | P51685 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27837532 | 0.82 | METAP2 (0.63) | NPC1METAP1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10429391 | 0.82 | NPC1 (0.42) | NPC1METAP1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL13504644 | 0.78 | NPC1 (0.50) | NPC1METAP1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL6883476 | 0.78 | ADORA3 (0.53) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL1989677 | 0.78 | NPC1 (0.40) | NPC1METAP1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL13469300 | 0.77 | PARP1 (0.53) | NPC1RAB9ASMN1; SMN2PKMHPGD | |
| SCHEMBL7749016 | 0.76 | EDNRA (0.39) | NPC1METAP1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL15450894 | 0.74 | KDM4E (0.51) | NPC1METAP1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL6368182 | 0.73 | PARP1 (0.47) | NPC1RAB9ASMN1; SMN2HPGDHTT | |
| SCHEMBL30427456 | 0.73 | NPC1 (0.59) | NPC1METAP1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101035787-B | Method for enantioselective preparation of sulphoxide derivatives | SIDEM PHARMA | 2013-03-27 | — | — | CN | disclosed |
| US-7528251-B2 | Method for enantioselective preparation of sulphoxide derivatives | SIDEM PHARMA SA (LU) | 2009-05-05 | — | — | US | disclosed |
| EP-1802620-B1 | METHOD FOR ENANTIOSELECTIVE PREPARATION OF SULPHOXIDE DERIVATIVES | SIDEM PHARMA S A (LU) | 2008-12-17 | — | — | EP | disclosed |
| US-20070299261-A1 | Method For Enantioselective Preparation Of Sulphoxide Derivatives | SIDEM PHARMA SA (LU) | 2007-12-27 | — | — | US | disclosed |
| CN-101035787-A | Method for enantioselective preparation of sulphoxide derivatives | SIDEM PHARMA (LU) | 2007-09-12 | — | — | CN | disclosed |
| EP-1802620-A1 | METHOD FOR ENANTIOSELECTIVE PREPARATION OF SULPHOXIDE DERIVATIVES | Sidem Pharma (LU) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006037894-A1 | METHOD FOR ENANTIOSELECTIVE PREPARATION OF SULPHOXIDE DERIVATIVES | SIDEM PHARMA S.A. (LU) | 2006-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299261-A1 | Method For Enantioselective Preparation Of Sulphoxide Derivatives | TST, ADH1A, ADH1C | NPC1 4784/4885METAP1 1713/4885LMNA 4312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.