Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MGAM | O43451 | 2/20 | 0.52 |
| ▸ | SI | P14410 | 2/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2701579 | 0.87 | GAA (0.60) | GAAMGAMSIMGAM2ALDH1A1 | |
| Water SCHEMBL2703341 | 0.84 | GAA (0.57) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL4465312 | 0.84 | ADRA2A (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10935011 | 0.84 | MGAM (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2184225 | 0.84 | MGAM (0.63) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL20022348 | 0.83 | ADRA2A (0.43) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10990781 | 0.82 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL649327 | 0.82 | MGAM (0.55) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL16411225 | 0.82 | MGAM (0.55) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL14573478 | 0.82 | ALDH1A1 (0.53) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295672-A1 | PROCESS FOR PRODUCING (R)-3-HYDROXYBUTYL (R)-3-HYDROXYBUTYRATE | UNIV OXFORD INNOVATION LTD (GB) | 2023-09-21 | — | — | US | disclosed |
| EP-2419519-B1 | PROCESS FOR PRODUCING (3R)-HYDROXYBUTYL (3R)-HYDROXYBUTYRATE BY ENZYMATIC ENANTIOSELECTIVE REDUCTION EMPLOYING ALCOHOL DEHYDROGENASES OR KETO REDUCTASES | UNIV OXFORD INNOVATION LTD (GB) | 2019-03-27 | — | — | EP | disclosed |
| EP-2419519-B1 | PROCESS FOR PRODUCING (3R)-HYDROXYBUTYL (3R)-HYDROXYBUTYRATE BY ENZYMATIC ENANTIOSELECTIVE REDUCTION EMPLOYING ALCOHOL DEHYDROGENASES OR KETO REDUCTASES | UNIV OXFORD INNOVATION LTD (GB) | 2019-03-27 | — | — | EP | disclosed |
| EP-2984066-B1 | PROCESS FOR PRODUCING (R)-3-HYDROXYBUTYL (R)-3-HYDROXYBUTYRATE | UNIV OXFORD INNOVATION LTD (GB) | 2017-02-01 | — | — | EP | disclosed |
| CN-103339112-B | Topical antifungal agents | MEIJI SEIKA PHARMA CO.,LTD. (JP) | 2015-08-12 | — | — | CN | disclosed |
| US-9034613-B2 | Process for the preparation of (3R)-hydroxybutyl (3R)-hydroxybutyrate by enzymatic enantioselective reduction employing Lactobacillus brevis alcohol dehydrogenase | ISIS INNOVATION LIMITED | 2015-05-19 | — | — | US | disclosed |
| US-9034613-B2 | Process for the preparation of (3R)-hydroxybutyl (3R)-hydroxybutyrate by enzymatic enantioselective reduction employing Lactobacillus brevis alcohol dehydrogenase | ISIS INNOVATION LIMITED | 2015-05-19 | — | — | US | disclosed |
| US-9034613-B2 | Process for the preparation of (3R)-hydroxybutyl (3R)-hydroxybutyrate by enzymatic enantioselective reduction employing Lactobacillus brevis alcohol dehydrogenase | ISIS INNOVATION LIMITED | 2015-05-19 | — | — | US | disclosed |
| US-8921306-B2 | Nociceptin mimetics | THE UNIVERSITY OF QUEENSLAND (AU) | 2014-12-30 | — | — | US | disclosed |
| US-20140308719-A1 | PROCESS FOR PRODUCING (R)-3-HYDROXYBUTYL (R)-3-HYDROXYBUTYRATE | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2014-10-16 | — | — | US | disclosed |
| CN-101821257-B | 5-HT7 receptor antagonists | LILLY CO ELI | 2013-05-22 | — | — | CN | disclosed |
| US-20120064611-A1 | Process For The Preparation of (3R)-Hydroxybutyl (3R) -Hydroxybutyrate By Enzymatic Enantioselective Reduction Employing Lactobacillus Brevis Alcohol Dehydrogenase | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2012-03-15 | — | — | US | disclosed |
| US-20120064611-A1 | Process For The Preparation of (3R)-Hydroxybutyl (3R) -Hydroxybutyrate By Enzymatic Enantioselective Reduction Employing Lactobacillus Brevis Alcohol Dehydrogenase | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2012-03-15 | — | — | US | disclosed |
| US-20120064611-A1 | Process For The Preparation of (3R)-Hydroxybutyl (3R) -Hydroxybutyrate By Enzymatic Enantioselective Reduction Employing Lactobacillus Brevis Alcohol Dehydrogenase | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2012-03-15 | — | — | US | disclosed |
| EP-2419519-A1 | PROCESS FOR THE PREPARATION OF (3R)-HYDR0XYBUTYL (3R) -HYDROXYBUTYRATE BY ENZYMATIC ENANTIOSELECTIVE REDUCTION EMPLOYING LACTOBACILLUS BREVIS ALCOHOL DEHYDROGENASE | Isis Innovation Limited (GB) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010120300-A1 | PROCESS FOR THE PREPARATION OF (3R)-HYDR0XYBUTYL (3R) -HYDROXYBUTYRATE BY ENZYMATIC ENANTIOSELECTIVE REDUCTION EMPLOYING LACTOBACILLUS BREVIS ALCOHOL DEHYDROGENASE | ISIS INNOVATION LIMITED (GB) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010120300-A1 | PROCESS FOR THE PREPARATION OF (3R)-HYDR0XYBUTYL (3R) -HYDROXYBUTYRATE BY ENZYMATIC ENANTIOSELECTIVE REDUCTION EMPLOYING LACTOBACILLUS BREVIS ALCOHOL DEHYDROGENASE | ISIS INNOVATION LIMITED (GB) | 2010-10-21 | — | — | WO | disclosed |
| CN-101448834-A | 2-arylpyrazolo [1, 5-alpha ] pyrimidin-3-ylacetamide derivatives as transporter (18kDa) ligands | UNIV SYDNEY (AU) | 2009-06-03 | — | — | CN | disclosed |
| CN-1221544-C | Pyrazole cyclic AMP-specific PDE inhibitors | ICOS CORP (US) | 2005-10-05 | — | — | CN | disclosed |
| CN-1434817-A | Pyrazole cyclic AMP-specific phosphodiesterase inhibitors | ICOS CORP (US) | 2003-08-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064611-A1 | Process For The Preparation of (3R)-Hydroxybutyl (3R) -Hydroxybutyrate By Enzymatic Enantioselective Reduction Employing Lactobacillus Brevis Alcohol Dehydrogenase | ADH5, ADH1A, ADH1C | GAA 1130/4885MGAM 261/4885SI 138/4885 |
| US-20230295672-A1 | PROCESS FOR PRODUCING (R)-3-HYDROXYBUTYL (R)-3-HYDROXYBUTYRATE | HCAR3, HSD17B12, HSD17B10 | GAA 1830/4885MGAM 336/4885SI 143/4885 |
| US-20140308719-A1 | PROCESS FOR PRODUCING (R)-3-HYDROXYBUTYL (R)-3-HYDROXYBUTYRATE | HCAR3, HSD17B12, HSD17B10 | GAA 1830/4885MGAM 336/4885SI 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.