Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581421 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAOBMEN1KMT2ARAB9A | |
| SCHEMBL393305 | 0.80 | SLC7A5 (0.48) | ALDH1A1TDP1 | |
| SCHEMBL105228 | 0.80 | ENPP2 (0.48) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28018484 | 0.79 | AKT1 (0.46) | ALDH1A1MAOBMEN1KMT2AHPGD | |
| SCHEMBL20221426 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAOBMEN1KMT2ARAB9A | |
| SCHEMBL6647903 | 0.76 | TSHR (0.45) | MEN1KMT2ALMNATDP1SMN1; SMN2 | |
| Acetic Acid SCHEMBL29130478 | 0.76 | ORAI1 (0.41) | ALDH1A1HPGDTDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL26345899 | 0.74 | ACHE (0.42) | ALDH1A1NPC1LMNACYP1A2MAPK1 | |
| SCHEMBL27903456 | 0.73 | MAOB (0.49) | ALDH1A1MAOBMEN1KMT2ARAB9A | |
| SCHEMBL522374 | 0.72 | ENPP2 (0.43) | ALDH1A1LMNASMN1; SMN2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517896-B2 | Aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2009-04-14 | — | — | US | disclosed |
| US-7087622-B2 | Pyridone compounds as inhibitors of bacterial type III protein secreation systems | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-08-08 | — | — | US | disclosed |
| US-20060094769-A1 | Novel aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2006-05-04 | — | — | US | disclosed |
| WO-2005110988-A1 | PYRIDONE COMPOUNDS AS INHIBITORS OF BACTERIAL TYPE III PROTEIN SECRETION SYSTEMS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-11-24 | — | — | WO | disclosed |
| US-20050256137-A1 | Pyridone compounds as inhibitors of bacterial type III protien secreation systems | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094769-A1 | Novel aminodicarboxylic acid derivatives having pharmaceutical properties | DDC, AADAT, PTGIS | ALDH1A1 214/4885MAOB 749/4885MEN1 4572/4885 |
| US-20050256137-A1 | Pyridone compounds as inhibitors of bacterial type III protien secreation systems | PROC, PSMB3, PANK3 | ALDH1A1 4777/4885MAOB 1496/4885MEN1 3331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.