Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | GRK2 | P25098 | 1/20 | 0.78 |
| ▸ | PLEC | Q15149 | 1/20 | 0.78 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 2/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.44 |
| ▸ | DUSP5 | Q16690 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30358116 | 1.00 | MEN1 (0.78) | MEN1KMT2APOLBGRK2PLEC | |
| SCHEMBL29381693 | 1.00 | MEN1 (0.78) | MEN1KMT2APOLBGRK2PLEC | |
| SCHEMBL4326683 | 1.00 | MEN1 (0.78) | MEN1KMT2APOLBGRK2PLEC | |
| SCHEMBL10893557 | 0.92 | MEN1 (0.64) | MEN1KMT2APOLBGRK2PLEC | |
| SCHEMBL10893544 | 0.92 | MEN1 (0.64) | MEN1KMT2APOLBGRK2PLEC | |
| SCHEMBL700390 | 0.88 | MEN1 (1.00) | MEN1KMT2APOLBGRK2PLEC | |
| SCHEMBL11754845 | 0.88 | MEN1 (1.00) | MEN1KMT2APOLBGRK2PLEC | |
| SCHEMBL29859205 | 0.88 | MEN1 (1.00) | MEN1KMT2APOLBGRK2PLEC | |
| SCHEMBL16143830 | 0.86 | PRMT1 (0.67) | MEN1KMT2APOLBGRK2PLEC | |
| SCHEMBL16143776 | 0.86 | PRMT1 (0.67) | MEN1KMT2APOLBGRK2PLEC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12287283-B2 | Linearized optical sensor calibration for measuring calcium | ECOLAB USA INC. (US) | 2025-04-29 | — | — | US | disclosed |
| EP-4172595-A1 | LINEARIZED OPTICAL SENSOR CALIBRATION FOR MEASURING CALCIUM | Ecolab USA Inc. (US) | 2023-05-03 | — | — | EP | disclosed |
| WO-2022006234-A1 | LINEARIZED OPTICAL SENSOR CALIBRATION FOR MEASURING CALCIUM | ECOLAB USA INC. (US) | 2022-01-06 | — | — | WO | disclosed |
| US-20210404950-A1 | LINEARIZED OPTICAL SENSOR CALIBRATION FOR MEASURING CALCIUM | ECOLAB USA INC. | 2021-12-30 | — | — | US | disclosed |
| EP-1615029-B1 | Reagent and method for determination of calcium | NITTO BOSEKI CO LTD (JP) | 2014-10-08 | — | — | EP | disclosed |
| US-7544516-B2 | Reagent for determination of calcium and determination method | NITTO BOSEKI CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-20060008915-A1 | Reagent for determination of calcium and determination method | NITTO BOSEKI CO., LTD. (JP) | 2006-01-12 | — | — | US | disclosed |
| EP-1615029-A2 | Reagent and method for determination of calcium | NITTO BOSEKI CO., LTD. (JP) | 2006-01-11 | — | — | EP | disclosed |