Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ZAP70 | P43403 | 6/20 | 0.31 |
| ▸ | KARS1 | Q15046 | 6/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13236205 | 0.79 | NPSR1 (0.37) | KMT2ARXFP1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5959166 | 0.79 | KMT2A (0.34) | KMT2ARXFP1ZAP70KARS1SYK | |
| SCHEMBL2942781 | 0.78 | PTGDR2 (0.36) | KMT2ARXFP1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6016955 | 0.75 | DHPS (0.42) | KMT2ARXFP1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL12415747 | 0.69 | TLR7 (0.34) | KMT2ARXFP1ZAP70KARS1ALK | |
| SCHEMBL6016956 | 0.68 | DHPS (0.37) | RXFP1KDM4EHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL13236218 | 0.68 | ALDH1A1 (0.37) | KMT2ARXFP1ZAP70KARS1SYK | |
| SCHEMBL2945205 | 0.67 | GABRP (0.38) | KMT2ARXFP1KDM4EHPGDZAP70 | |
| SCHEMBL13264544 | 0.67 | L3MBTL1 (0.32) | KDM4ENPSR1ALK | |
| SCHEMBL1923032 | 0.65 | PTGDR2 (0.39) | KMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718649-B1 | IMIDAZO 1,2-C PYRIMIDINYLACETIC ACID DERIVATIVES | ACTIMIS PHARMACEUTICALS INC (US) | 2009-06-10 | — | — | EP | disclosed |