Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333426 | 0.87 | ALDH1A1 (0.48) | F2RL3MAPTKDM4EGAAMEN1 | |
| SCHEMBL4330806 | 0.83 | CAMK2D (0.45) | F2RL3MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL13577950 | 0.81 | MAPK1 (0.45) | MAPTRAB9AGAAMEN1KMT2A | |
| SCHEMBL13577954 | 0.80 | DRD2 (0.45) | F2RL3MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL13577941 | 0.80 | ASH1L (0.48) | F2RL3MEN1KMT2AHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL4326712 | 0.79 | ASH1L (0.47) | F2RL3MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL13577956 | 0.78 | LMNA (0.47) | MAPTRAB9AKDM4EMEN1KMT2A | |
| SCHEMBL4326615 | 0.77 | SCN9A (0.49) | F2RL3MAPTKDM4EGAAMEN1 | |
| SCHEMBL4324539 | 0.76 | SCN9A (0.44) | F2RL3MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL4335986 | 0.75 | NPC1 (0.47) | MAPTRAB9AHPGDSCN9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |