Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4336992 | 0.91 | LMNA (0.52) | RAB9ANPC1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9620186 | 0.78 | CES2 (0.47) | RAB9ANPC1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL18934701 | 0.75 | LMNA (0.56) | RAB9ANPC1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL4341948 | 0.74 | ALDH1A1 (0.48) | RAB9ANPC1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL4345805 | 0.74 | CES2 (0.47) | RAB9ANPC1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL455188 | 0.74 | CES2 (0.50) | RAB9ANPC1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL2901449 | 0.74 | LMNA (0.54) | RAB9ANPC1MAPTSMN1; SMN2NPSR1 | |
| Styrene SCHEMBL27267441 | 0.73 | ALDH1A1 (0.45) | RAB9ANPC1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL755762 | 0.72 | LMNA (0.63) | RAB9ANPC1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL23416475 | 0.71 | L3MBTL1 (0.43) | RAB9ANPC1MAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026380-A1 | MEDICAL DEVICE WITH BIOFUNCTIONALIZED POLYMER COATING | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2009-02-26 | — | — | WO | claimed |
| WO-2009026380-A1 | MEDICAL DEVICE WITH BIOFUNCTIONALIZED POLYMER COATING | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2009-02-26 | — | — | WO | disclosed |