Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL22260994 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL136879 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL7672700 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL60726 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL6019667 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL16178480 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL29126608 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL20507993 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28800951 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL21182365 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122032475-A | Preparation and application of magnesium-iron-aluminum ternary layered double hydroxide loaded modified activated carbon composite material | 西南科技大学 | 2026-05-15 | — | — | CN | claimed |
| US-20260029170-A1 | METHODS, SYSTEMS, AND DEVICES FOR IONOCALORIC HEATING AND COOLING | UNIV CALIFORNIA (US) | 2026-01-29 | — | — | US | claimed |
| US-20250249440-A1 | PROCESS AND CATALYST FOR CATALYTIC CRACKING OF NAPHTHA TO LIGHT OLEFINS AND AROMATICS | HINDUSTAN PETROLEUM CORPORATION LIMITED (IN) | 2025-08-07 | — | — | US | claimed |
| CN-120138979-A | High-purity fiber for cellulose-based negative electrode of lithium battery and preparation method of high-purity fiber | 安徽雪龙新材料(集团)有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-119773017-A | Timber colorant based on metal-ligand coordination and application thereof | 中国科学院理化技术研究所 | 2025-04-08 | — | — | CN | claimed |
| CN-119430227-A | Prussian blue positive electrode material and preparation method thereof | 浙江工业大学 | 2025-02-14 | — | — | CN | claimed |
| CN-119303621-A | Perovskite dehydrogenation catalyst, preparation method thereof and method for producing low-carbon olefin | 中国石油化工股份有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-119039942-A | Inorganic hydrated salt heat storage phase change fiber and preparation method thereof | 广东工业大学 | 2024-11-29 | — | — | CN | claimed |
| CN-118422258-A | Ni for high-efficiency seawater electrolysis2P@NiFeS/NF catalyst and preparation method and application thereof | 中国科学院青岛生物能源与过程研究所 | 2024-08-02 | — | — | CN | claimed |
| WO-2024155294-A2 | METHODS, SYSTEMS, AND DEVICES FOR IONOCALORIC HEATING AND COOLING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-25 | — | — | WO | claimed |
| CN-101896267-A | Mixed manganese ferrite catalyst, preparation method thereof and method for preparing 1, 3-butadiene by using same | SK ENERGY CO LTD | 2010-11-24 | — | — | CN | claimed |
| US-20100280300-A1 | MIXED MANGANESE FERRITE CATALYSTS, METHOD OF PREPARING THEREOF AND METHOD OF PREPARING 1,3-BUTADIENE USING THEREOF | SK ENERGY CO., LTD (KR) | 2010-11-04 | — | — | US | claimed |
| EP-2219782-A2 | MIXED MANGANESE FERRITE CATALYSTS, METHOD OF PREPARING THEREOF AND METHOD OF PREPARING 1,3-BUTADIENE USING THEREOF | SK Energy Co., Ltd. (KR) | 2010-08-25 | — | — | EP | claimed |
| WO-2009075478-A2 | MIXED MANGANESE FERRITE CATALYSTS, METHOD OF PREPARING THEREOF AND METHOD OF PREPARING 1,3-BUTADIENE USING THEREOF | SK ENERGY CO., LTD. (KR) | 2009-06-18 | — | — | WO | claimed |
| US-5788990-A | Water-repellent powder and manufacture of the same | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1998-08-04 | — | — | US | claimed |
| EP-0422105-B1 | METAL OXIDE CERAMIC POWDERS AND METHODS OF MAKING SAME | BATTELLE MEMORIAL INSTITUTE (US) | 1994-09-07 | — | — | EP | claimed |
| US-5114702-A | Method of making metal oxide ceramic powders by using a combustible amino acid compound | BATTELLE MEMORIAL INSTITUTE (US) | 1992-05-19 | — | — | US | claimed |
| EP-0422105-A4 | METAL OXIDE CERAMIC POWDERS AND THIN FILMS AND METHODS OF MAKING SAME | — | 1992-01-08 | — | — | EP | claimed |
| EP-0422105-A1 | METAL OXIDE CERAMIC POWDERS AND METHODS OF MAKING SAME. | BATTELLE MEMORIAL INSTITUTE (US) | 1991-04-17 | — | — | EP | claimed |
| WO-1989012027-A1 | METAL OXIDE CERAMIC POWDERS AND THIN FILMS AND METHODS OF MAKING SAME | BATTELLE MEMORIAL INSTITUTE (US) | 1989-12-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260029170-A1 | METHODS, SYSTEMS, AND DEVICES FOR IONOCALORIC HEATING AND COOLING | CA2, SLC9A2, HSF1 | MEN1 895/4885KMT2A 2048/4885CA5A 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.