SCHEMBL434594

SCHEMBL434594

C#CCN(C)c1c(C)cc(OC(=O)NC)cc1C

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAF1 P04049 4/20 0.39
ACHE P22303 9/20 0.38
BCHE P06276 3/20 0.38
CYP1A2 P05177 1/20 0.34
CYP2C8 P10632 1/20 0.34
CYP2B6 P20813 1/20 0.34
KDM4E B2RXH2 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MMP1 P03956 1/20 0.33
MMP9 P14780 1/20 0.33
MMP13 P45452 1/20 0.33
ADAM17 P78536 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11509949 0.88 RAF1 (0.39) RAF1ACHEBCHECYP1A2CYP2C8
SCHEMBL1069070 0.83 KDM4E (0.36) ACHEBCHECYP1A2CYP2C8CYP2B6
Mexacarbate SCHEMBL121459 0.79 ACHE (0.44) RAF1ACHEBCHEKDM4EKMT2A
Mexacarbate SCHEMBL6738142 0.79 ACHE (0.44) RAF1ACHEBCHEKDM4EKMT2A
SCHEMBL11509648 0.79 ACHE (0.41) ACHEBCHECYP1A2CYP2C8CYP2B6
SCHEMBL11510111 0.78 RAF1 (0.38) RAF1ACHEBCHECYP1A2KDM4E
SCHEMBL11307820 0.78 RAF1 (0.40) RAF1ACHEBCHEKDM4EKMT2A
SCHEMBL5184928 0.77 CYP1A2 (0.44) CYP1A2CYP2C8CYP2B6KDM4EKMT2A
Mexacarbate SCHEMBL7532034 0.76 RAF1 (0.45) RAF1ACHEBCHECYP1A2KDM4E
SCHEMBL11508357 0.76 RAF1 (0.41) RAF1ACHEBCHECYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1490 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
US-20250017207-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-01-16 US claimed
EP-4422404-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2024-09-04 EP claimed
EP-4422402-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL Syngenta Crop Protection AG (CH) 2024-09-04 EP claimed
WO-2023072785-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 WO claimed
WO-2023072784-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 WO claimed
WO-2020127319-A1 PLANT GROWTH REGULATOR COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-06-25 WO claimed
EP-2347655-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS Syngenta Participations AG. (CH) 2011-07-27 EP claimed
EP-2332411-A1 Fungicidal compositions Syngenta Participations AG (CH) 2011-06-15 EP claimed
JP-2008509189-A 2008-03-27 JP claimed
US-20080076664-A1 Fungicidal Compositions SYNGENTA CROP PROTECTION, INC. 2008-03-27 US claimed
US-20080070785-A1 For controlling phytopathogenic diseases; synergistic SYNGENTA CROP PROTECTION, INC. (US) 2008-03-20 US claimed
US-20070244121-A1 Synergistic Fungicidal Compositions SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 US claimed
EP-1796464-A1 FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-06-20 EP claimed
EP-1778013-A1 FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-05-02 EP claimed
WO-2007009661-A2 PESTICIDAL MIXTURES CONTAINING BICYCLIC ANTHRANILAMIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-01-25 WO claimed
WO-2006037634-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 WO claimed
WO-2006015865-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-02-16 WO claimed
EP-4747241-A1 BENZIMIDAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-05-27 EP disclosed
US-3932630-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250017207-A1 FUNGICIDAL COMPOSITIONS CYP51A1, BROX, DPM1 RAF1 4090/4885ACHE 911/4885BCHE 311/4885
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL NOTUM, CTRL, BROX RAF1 3311/4885ACHE 102/4885BCHE 94/4885
US-20070244121-A1 Synergistic Fungicidal Compositions DDT, CRY1, HCN1 RAF1 2264/4885ACHE 549/4885BCHE 346/4885
US-20080070785-A1 For controlling phytopathogenic diseases; synergistic BROX, EPM2A, MANBA RAF1 2739/4885ACHE 551/4885BCHE 143/4885
US-20080076664-A1 Fungicidal Compositions AKR7A2, CYP51A1, TUBA3C RAF1 1374/4885ACHE 732/4885BCHE 213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.