Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964422 | 0.94 | PPARG (0.42) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL433061 | 0.94 | PPARG (0.42) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL14962075 | 0.88 | LMNA (0.52) | LMNATOP2ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL433489 | 0.87 | LMNA (0.51) | LMNATOP2ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL431303 | 0.80 | NAAA (0.39) | LMNASMN1; SMN2KDM4EKMT2AHPGD | |
| SCHEMBL15943384 | 0.78 | LMNA (0.46) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL11822590 | 0.73 | TDP1 (0.48) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL11880693 | 0.71 | TDP1 (0.44) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL7393115 | 0.71 | MMP9 (0.51) | SMN1; SMN2KDM4EMEN1KMT2AALOX5 | |
| SCHEMBL434346 | 0.70 | ALDH1A1 (0.57) | LMNASMN1; SMN2KDM4EKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003242-B | Pyridin-2-ylsulfanyl esters and methods of making the same | COUNCIL SCIENT IND RES | 2015-04-22 | — | — | CN | claimed |
| EP-2595957-B1 | PYRIDIN-2-YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2014-08-13 | — | — | EP | claimed |
| US-8680288-B2 | Pyridin-2yl sulfanyl acid esters and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-03-25 | — | — | US | claimed |
| EP-2595957-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2013-05-29 | — | — | EP | claimed |
| US-20130131350-A1 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-23 | — | — | US | claimed |
| CN-103003242-A | Pyridin-2-ylsulfanyl esters and methods of making the same | COUNCIL SCIENT IND RES | 2013-03-27 | — | — | CN | claimed |
| WO-2012011123-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | WO | claimed |
| CN-103003242-B | Pyridin-2-ylsulfanyl esters and methods of making the same | COUNCIL SCIENT IND RES | 2015-04-22 | — | — | CN | disclosed |
| EP-2595957-B1 | PYRIDIN-2-YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2014-08-13 | — | — | EP | disclosed |
| EP-2595957-B1 | PYRIDIN-2-YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2014-08-13 | — | — | EP | disclosed |
| US-8680288-B2 | Pyridin-2yl sulfanyl acid esters and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-03-25 | — | — | US | disclosed |
| US-8680288-B2 | Pyridin-2yl sulfanyl acid esters and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-03-25 | — | — | US | disclosed |
| US-8680288-B2 | Pyridin-2yl sulfanyl acid esters and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-03-25 | — | — | US | disclosed |
| EP-2595957-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2013-05-29 | — | — | EP | disclosed |
| US-20130131350-A1 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-23 | — | — | US | disclosed |
| US-20130131350-A1 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-23 | — | — | US | disclosed |
| US-20130131350-A1 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-23 | — | — | US | disclosed |
| CN-103003242-A | Pyridin-2-ylsulfanyl esters and methods of making the same | COUNCIL SCIENT IND RES | 2013-03-27 | — | — | CN | disclosed |
| WO-2012011123-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012011123-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131350-A1 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | VCAM1, ICAM1, CCL5 | LMNA 1729/4885TOP2A 3775/4885SMN1; SMN2 2409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.