Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329711 | 0.86 | CYSLTR1 (0.49) | — | |
| SCHEMBL4339537 | 0.84 | HDAC1 (0.40) | FFAR1EPHX1TNKSTNKS2 | |
| SCHEMBL4334154 | 0.82 | LMNA (0.44) | CASP1FFAR1MEN1KMT2A | |
| SCHEMBL4348234 | 0.82 | PPARG (0.40) | EPHX1PTGESTNKSTNKS2MEN1 | |
| SCHEMBL4348238 | 0.82 | PPARG (0.40) | EPHX1PTGESTNKSTNKS2MEN1 | |
| SCHEMBL4342514 | 0.81 | ALDH1A1 (0.42) | FFAR1CASP3 | |
| SCHEMBL4334667 | 0.80 | NPC1 (0.49) | CASP1FFAR1KMT2A | |
| SCHEMBL4337917 | 0.80 | NR3C2 (0.45) | — | |
| SCHEMBL4328963 | 0.80 | PTGDR2 (0.47) | FFAR1 | |
| SCHEMBL4332643 | 0.79 | CASP1 (0.42) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100522944-C | Carboxylic acid derivatives and salts thereof | EISAI CO LTD (JP) | 2009-08-05 | — | — | CN | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| CN-1503774-A | Carboxylic acid derivatives and salts thereof | ������������ʽ���� | 2004-06-09 | — | — | CN | disclosed |