Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334154 | 0.85 | LMNA (0.44) | TSHRALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4342514 | 0.84 | ALDH1A1 (0.42) | TSHRALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4348232 | 0.84 | CASP1 (0.36) | EPHX1TNKSTNKS2FFAR1 | |
| SCHEMBL4334667 | 0.83 | NPC1 (0.49) | TSHRKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4328963 | 0.83 | PTGDR2 (0.47) | FFAR1 | |
| SCHEMBL4329062 | 0.82 | MAPT (0.48) | ALDH1A1CYP2C19SMN1; SMN2FFAR1L3MBTL1 | |
| SCHEMBL4339539 | 0.82 | HDAC1 (0.41) | HDAC1NAMPTHDAC3HDAC4HDAC7 | |
| SCHEMBL4332643 | 0.82 | CASP1 (0.42) | TSHRALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4339541 | 0.82 | HDAC1 (0.41) | HDAC1NAMPTHDAC3HDAC4HDAC7 | |
| SCHEMBL4337917 | 0.81 | NR3C2 (0.45) | KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |