Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 6/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334154 | 0.88 | LMNA (0.44) | CASP1PLAUCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4342514 | 0.87 | ALDH1A1 (0.42) | PLAUCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4329062 | 0.87 | MAPT (0.48) | NAAAASAH1CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL4334667 | 0.86 | NPC1 (0.49) | CASP1PLAUCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4328963 | 0.85 | PTGDR2 (0.47) | — | |
| SCHEMBL4331854 | 0.83 | OPRM1 (0.44) | MAPT | |
| SCHEMBL4339537 | 0.82 | HDAC1 (0.40) | PLAUCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4337917 | 0.82 | NR3C2 (0.45) | TGM2LMNA | |
| SCHEMBL4332639 | 0.82 | PPARG (0.44) | TGM2PLAUNAAAASAH1ALDH1A1 | |
| SCHEMBL4332646 | 0.82 | PPARG (0.44) | TGM2PLAUNAAAASAH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |