Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 5/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4353987 | 1.00 | MAPT (0.61) | MAPTKDM4EHTTLMNANPC1 | |
| SCHEMBL19393344 | 0.92 | CA12 (0.71) | MAPTKDM4EHTTLMNANPC1 | |
| SCHEMBL14354242 | 0.91 | CA2 (0.59) | MAPTKDM4EHTTLMNANPC1 | |
| SCHEMBL14354241 | 0.91 | CA2 (0.59) | MAPTKDM4EHTTLMNANPC1 | |
| SCHEMBL10061910 | 0.90 | MAPT (0.55) | MAPTKDM4EHTTLMNANPC1 | |
| SCHEMBL28243912 | 0.90 | MAPT (0.54) | MAPTKDM4EHTTLMNANPC1 | |
| Acetic Acid SCHEMBL1229395 | 0.89 | MAPT (0.50) | MAPTKDM4EHTTLMNANPC1 | |
| SCHEMBL16660367 | 0.88 | MAPT (0.53) | MAPTKDM4EHTTLMNANPC1 | |
| Acetic Acid SCHEMBL1229559 | 0.83 | MAPT (0.48) | MAPTKDM4EHTTLMNANPC1 | |
| SCHEMBL23629776 | 0.81 | MAPT (0.53) | MAPTKDM4EHTTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10034941-B2 | Iron-salen complex | IHI CORPORATION (JP) | 2018-07-31 | — | — | US | disclosed |
| US-9475762-B2 | Process for the preparation of urethanes | COVESTRO DEUTSCHLAND AG (DE) | 2016-10-25 | — | — | US | disclosed |
| US-20160193337-A1 | IRON-SALEN COMPLEX | ISHIKAWA, YOSHIHIRO (JP) | 2016-07-07 | — | — | US | disclosed |
| US-20160152559-A1 | PROCESS FOR THE PREPARATION OF URETHANES | COVESTRO DEUTSCHLAND AG (DE) | 2016-06-02 | — | — | US | disclosed |
| US-9284267-B2 | Process for the preparation of urethanes | BAYER MATERIALSCIENCE AG (DE) | 2016-03-15 | — | — | US | disclosed |
| US-20090275771-A1 | Process for the preparation of urethanes | COVESTRO DEUTSCHLAND AG (DE) | 2009-11-05 | — | — | US | disclosed |
| US-5281578-A | Pharmaceutical gallium metal complex in mixture with carrier | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1994-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152559-A1 | PROCESS FOR THE PREPARATION OF URETHANES | OGG1, SOD1, DUOX2 | MAPT 1596/4885KDM4E 288/4885HTT 2418/4885 |
| US-10034941-B2 | Iron-salen complex | SLC40A1, SDHB, TFRC | MAPT 1228/4885KDM4E 2864/4885HTT 990/4885 |
| US-20160193337-A1 | IRON-SALEN COMPLEX | SLC40A1, SDHB, TFRC | MAPT 1228/4885KDM4E 2864/4885HTT 990/4885 |
| US-20090275771-A1 | Process for the preparation of urethanes | OGG1, SOD1, DUOX2 | MAPT 1596/4885KDM4E 288/4885HTT 2418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.