Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | FABP6 | P51161 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | TXN | P10599 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348250 | 0.79 | LMNA (0.39) | ALDH1A1POLBRAB9AKMT2AHTT | |
| SCHEMBL4350354 | 0.78 | MPO (0.38) | ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL4352227 | 0.78 | HRH4 (0.35) | ALDH1A1POLBKMT2AHTTLMNA | |
| SCHEMBL4356635 | 0.78 | HRH4 (0.47) | ALDH1A1POLBSMN1; SMN2HTTLMNA | |
| SCHEMBL4355101 | 0.76 | ALDH1A1 (0.38) | ALDH1A1POLBRAB9ASMN1; SMN2HTR2B | |
| SCHEMBL4353639 | 0.74 | KDM4E (0.40) | ALDH1A1POLBRAB9ASMN1; SMN2FABP6 | |
| SCHEMBL4354354 | 0.73 | HRH4 (0.44) | ALDH1A1HPGDNPY5RCYP1A2CYP2C9 | |
| SCHEMBL4356646 | 0.73 | HRH4 (0.45) | SMN1; SMN2HTTLMNACYP1A2HIF1A | |
| SCHEMBL602574 | 0.72 | HRH4 (0.68) | ALDH1A1POLBHPGDCYP2C9 | |
| SCHEMBL1108966 | 0.70 | ALDH1A1 (0.78) | ALDH1A1POLBHPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504426-B2 | Heterocyclic compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-17 | — | — | US | disclosed |