Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348250 | 0.84 | LMNA (0.39) | ALDH1A1MCHR1HRH4POLBCYP1A2 | |
| SCHEMBL4356635 | 0.83 | HRH4 (0.47) | ALDH1A1MCHR1NPSR1HRH4POLB | |
| SCHEMBL4350354 | 0.83 | MPO (0.38) | ALDH1A1HRH4KMT2AHRH3 | |
| SCHEMBL4352227 | 0.83 | HRH4 (0.35) | ALDH1A1HRH4POLBMEN1KMT2A | |
| SCHEMBL4353639 | 0.79 | KDM4E (0.40) | ALDH1A1POLBCYP1A2CYP2C19MEN1 | |
| SCHEMBL4356646 | 0.78 | HRH4 (0.45) | HRH4CYP1A2MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL4354354 | 0.78 | HRH4 (0.44) | ALDH1A1HRH4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL4354372 | 0.76 | ALDH1A1 (0.42) | ALDH1A1POLBCYP1A2KMT2ACYP2C9 | |
| SCHEMBL4103942 | 0.75 | KCNH2 (0.40) | HRH4 | |
| SCHEMBL26937270 | 0.73 | HCRTR1 (0.48) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504426-B2 | Heterocyclic compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-17 | — | — | US | disclosed |