Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347885 | 0.88 | GPR119 (0.37) | GPR119PIK3CAHDAC4LMNAFASN | |
| SCHEMBL4355169 | 0.88 | PTPN2 (0.44) | GPR119HDAC4PTPN1 | |
| SCHEMBL13586029 | 0.87 | PTPN2 (0.44) | PIK3CALMNAFASNPOLBPTPN1 | |
| SCHEMBL4524446 | 0.85 | GPR119 (0.40) | GPR119POLBHPGD | |
| SCHEMBL4356470 | 0.82 | GPR119 (0.38) | GPR119HDAC4HRH3L3MBTL1 | |
| SCHEMBL4355595 | 0.78 | POLB (0.54) | LMNAFASNPOLBPTPN1HPGD | |
| SCHEMBL4357683 | 0.78 | POLB (0.48) | GPR119BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL4520212 | 0.78 | PTPN2 (0.47) | PIK3CALMNAFASNPOLBPTPN1 | |
| SCHEMBL13586034 | 0.78 | ABL1 (0.46) | GPR119HDAC4POLBPTPN1 | |
| SCHEMBL4540972 | 0.77 | GPR119 (0.47) | GPR119HDAC4LMNAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |