Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586029 | 0.93 | PTPN2 (0.44) | PIK3CAPTPN1PTPN2SMN1; SMN2MGLL | |
| SCHEMBL4357683 | 0.88 | POLB (0.48) | GPR119PTPN1PTPN2SMN1; SMN2HPGD | |
| SCHEMBL4533028 | 0.88 | HPGD (0.41) | PIK3CAHPGDKMT2AALDH1A1POLB | |
| SCHEMBL4356480 | 0.88 | GPR119 (0.38) | GPR119PIK3CAPTPN1HDAC4HPGD | |
| SCHEMBL4524446 | 0.87 | GPR119 (0.40) | GPR119MEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL4355169 | 0.86 | PTPN2 (0.44) | GPR119PTPN1PTPN2HDAC4 | |
| SCHEMBL4535866 | 0.86 | GPR119 (0.36) | GPR119PIK3CASMN1; SMN2CYP2C19 | |
| SCHEMBL4356470 | 0.84 | GPR119 (0.38) | GPR119HDAC4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4520212 | 0.84 | PTPN2 (0.47) | PIK3CAPTPN1PTPN2SMN1; SMN2MGLL | |
| SCHEMBL4538463 | 0.83 | NPY2R (0.39) | GPR119TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |