Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4356470 | 0.92 | GPR119 (0.38) | GPR119KMT2AMEN1CYP2C19SETD7 | |
| SCHEMBL4356808 | 0.90 | SETD7 (0.45) | GPR119KMT2AMEN1CYP2C19GAA | |
| SCHEMBL4355169 | 0.89 | PTPN2 (0.44) | GPR119 | |
| SCHEMBL4360439 | 0.88 | TSHR (0.44) | GPR119KMT2AMEN1GAAHPGD | |
| SCHEMBL4347885 | 0.87 | GPR119 (0.37) | GPR119KMT2AMEN1CYP2C19HPGD | |
| SCHEMBL4523222 | 0.87 | GPR119 (0.39) | GPR119KMT2AMEN1CYP2C19GAA | |
| SCHEMBL4534565 | 0.86 | KDM4E (0.40) | GPR119KMT2AGAAHPGDKDM4E | |
| SCHEMBL13586029 | 0.86 | PTPN2 (0.44) | KMT2AMEN1CYP2C19HPGDALDH1A1 | |
| SCHEMBL4531625 | 0.86 | ALDH1A1 (0.40) | GAAKDM4ENPSR1ALDH1A1 | |
| SCHEMBL4349657 | 0.85 | GPR119 (0.44) | GPR119GAAKDM4ENPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |