Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4352615 | 0.92 | POLB (0.39) | GPR119HRH3KMT2AMEN1CYP2C19 | |
| SCHEMBL4524446 | 0.92 | GPR119 (0.40) | GPR119KMT2AMEN1CYP2C19SETD7 | |
| SCHEMBL4534628 | 0.90 | GPR119 (0.40) | GPR119 | |
| SCHEMBL4522943 | 0.88 | ALDH1A1 (0.36) | GPR119KMT2AMEN1 | |
| SCHEMBL4353425 | 0.88 | SCD5 (0.36) | GPR119HRH3KCNH2SMN1; SMN2 | |
| SCHEMBL4353651 | 0.86 | KCNH2 (0.38) | HRH3KMT2AMEN1HTR1ASLC6A4 | |
| SCHEMBL4350015 | 0.86 | GPR119 (0.41) | GPR119HRH3KMT2AMEN1HTR1A | |
| SCHEMBL4355169 | 0.86 | PTPN2 (0.44) | GPR119HDAC4ABL1RIN1 | |
| SCHEMBL4350129 | 0.85 | KDM4E (0.37) | GPR119SMN1; SMN2 | |
| SCHEMBL4347885 | 0.84 | GPR119 (0.37) | GPR119KMT2AMEN1HDAC4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |