SCHEMBL4355200

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5819528	1.00	SIGMAR1 (0.60)	SIGMAR1L3MBTL1MAPTALDH1A1HTT
	Hydrochloric Acid SCHEMBL31086290	0.98	SIGMAR1 (0.58)	SIGMAR1L3MBTL1MAPTALDH1A1HTT
	SCHEMBL11849805	0.89	SIGMAR1 (0.53)	SIGMAR1L3MBTL1MAPTALDH1A1HTT
	SCHEMBL6932504	0.83	L3MBTL1 (0.57)	SIGMAR1L3MBTL1MAPTALDH1A1HTT
	Hydrochloric Acid SCHEMBL9155467	0.83	SIGMAR1 (0.61)	SIGMAR1L3MBTL1MAPTALDH1A1HTT
	SCHEMBL27881567	0.82	MAPT (0.51)	SIGMAR1L3MBTL1MAPTALDH1A1HTT
	SCHEMBL17465576	0.82	L3MBTL1 (0.65)	SIGMAR1L3MBTL1MAPTALDH1A1HTT
	SCHEMBL28191143	0.82	L3MBTL1 (0.65)	SIGMAR1L3MBTL1MAPTALDH1A1HTT
	SCHEMBL20817230	0.82	SIGMAR1 (0.47)	SIGMAR1L3MBTL1MAPTALDH1A1HTT
	SCHEMBL476492	0.81	LMNA (0.46)	SIGMAR1ALDH1A1HTTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.