Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286761 | 0.86 | CMA1 (0.61) | PDE3BPDE3AALDH1A1PKMPGR | |
| SCHEMBL9484426 | 0.85 | PDE3B (0.68) | PDE3BPDE3AALDH1A1PKMPGR | |
| SCHEMBL9686038 | 0.84 | ALDH1A1 (0.51) | PDE3BPDE3AALDH1A1PKMPGR | |
| SCHEMBL9484422 | 0.79 | ALDH1A1 (0.50) | PDE3BPDE3AALDH1A1PKMPGR | |
| SCHEMBL9204486 | 0.79 | MAPT (0.59) | PDE3BPDE3AALDH1A1PKMPGR | |
| SCHEMBL11344106 | 0.77 | PDE3B (0.52) | PDE3BPDE3AALDH1A1PKMPGR | |
| SCHEMBL7257829 | 0.76 | ESR1 (0.46) | PDE3BPDE3AALDH1A1PKMPGR | |
| SCHEMBL9684901 | 0.76 | PDE3B (0.51) | PDE3BPDE3APGRCMA1MAPT | |
| SCHEMBL7709830 | 0.75 | PDE3B (0.55) | PDE3BPDE3AALDH1A1PKMPGR | |
| SCHEMBL20106905 | 0.75 | PDE3B (0.55) | PDE3BPDE3AALDH1A1PKMPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022213-A1 | Medicaments containing benzothiazole-2(3H)-one derivatives | Dr. Karl Thomae GmbH (DE) | 1981-01-14 | — | — | EP | claimed |
| US-20240294482-A1 | METHOD FOR CATALYTICALLY ACTIVATING CARBON DIOXIDE AS CARBONYLATION REAGENT WITH INORGANIC SULFUR | INNER MONGOLIA UNIVERSITY OF TECHNOLOGY (CN) | 2024-09-05 | — | — | US | disclosed |
| WO-2024020084-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-25 | — | — | WO | disclosed |
| EP-3875151-B1 | ALPHA-METHYL-SUBSTITUTED DIAZABICYCLO [4.3.1] DECANE DERIVATES FOR TREATMENT OF PSYCHIATRIC DISORDERS | UNIV DARMSTADT TECH (DE) | 2023-09-20 | — | — | EP | disclosed |
| CN-116745273-A | Method for catalyzing and activating carbon dioxide by using inorganic sulfur as carbonylation reagent | 内蒙古工业大学 | 2023-09-12 | — | — | CN | disclosed |
| US-20230126391-A1 | ALPHA-METHYL-SUBSTITUTED DIAZABICYCLO[4.3.1] DECANE DERIVATIVES FOR TREATMENT OF PSYCHIATRIC DISORDERS | Technische Universität Darmstadt (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20230126391-A1 | ALPHA-METHYL-SUBSTITUTED DIAZABICYCLO[4.3.1] DECANE DERIVATIVES FOR TREATMENT OF PSYCHIATRIC DISORDERS | Technische Universität Darmstadt (DE) | 2023-04-27 | — | — | US | disclosed |
| WO-2022135355-A1 | METHOD FOR CATALYTICALLY ACTIVATING CARBON DIOXIDE AS CARBONYLATION REAGENT WITH INORGANIC SULFUR | 内蒙古工业大学 | 2022-06-30 | — | — | WO | disclosed |
| WO-2022135355-A1 | METHOD FOR CATALYTICALLY ACTIVATING CARBON DIOXIDE AS CARBONYLATION REAGENT WITH INORGANIC SULFUR | 内蒙古工业大学 | 2022-06-30 | — | — | WO | disclosed |
| CN-114644603-A | Method for catalytically activating carbon dioxide as carbonylation reagent by using inorganic sulfur | 内蒙古工业大学 | 2022-06-21 | — | — | CN | disclosed |
| EP-1043319-A1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |
| EP-0462831-B1 | Bicyclic pyran derivatives and their use as inhibitors of 5-lipoxygenase | ZENECA LTD (GB) | 1996-02-28 | — | — | EP | disclosed |
| US-5462953-A | Benzoxazolyl derivatives useful as 5-lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-10-31 | — | — | US | disclosed |
| US-5364877-A | Antiinflammatory agents, antiallergens | ICI PHARMA (GB) | 1994-11-15 | — | — | US | disclosed |
| US-5278177-A | Enzyme inhibitory | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-11 | — | — | US | disclosed |
| US-5179115-A | Antiinflammatory agents, antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-12 | — | — | US | disclosed |
| EP-0462831-A2 | Bicyclic pyran derivatives and their use as inhibitors of 5-lipoxygenase | ZENECA LIMITED (GB) | 1991-12-27 | — | — | EP | disclosed |
| US-4328235-A | SUPPRESSION OF PAIN | BOEHRINGER INGELHEIM GMBH (DE) | 1982-05-04 | — | — | US | disclosed |
| EP-0003035-B1 | PROCESS FOR THE PREPARATION OF POLYMERS OF VINYL CHLORIDE AND REACTOR FOR CARRYING OUT THE PROCESS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-24 | — | — | EP | disclosed |
| EP-0022213-A1 | Medicaments containing benzothiazole-2(3H)-one derivatives | Dr. Karl Thomae GmbH (DE) | 1981-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294482-A1 | METHOD FOR CATALYTICALLY ACTIVATING CARBON DIOXIDE AS CARBONYLATION REAGENT WITH INORGANIC SULFUR | TST, CBR3, SMOX | PDE3B 4085/4885PDE3A 4059/4885ALDH1A1 639/4885 |
| US-20230126391-A1 | ALPHA-METHYL-SUBSTITUTED DIAZABICYCLO[4.3.1] DECANE DERIVATIVES FOR TREATMENT OF PSYCHIATRIC DISORDERS | FKBP8, FKBP2, FKBP1A | PDE3B 3855/4885PDE3A 2791/4885ALDH1A1 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.