Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4534565 | 0.91 | KDM4E (0.40) | TSHRALDH1A1MAPTKMT2AGAA | |
| SCHEMBL4534628 | 0.90 | GPR119 (0.40) | TSHRGPR119CHRM2 | |
| SCHEMBL4531625 | 0.90 | ALDH1A1 (0.40) | ALDH1A1MAPTGAAKDM4ELMNA | |
| SCHEMBL4356808 | 0.89 | SETD7 (0.45) | ALDH1A1MEN1KMT2AGAAGPR119 | |
| SCHEMBL4349657 | 0.89 | GPR119 (0.44) | ALDH1A1GAAGPR119KDM4ECHRM2 | |
| SCHEMBL4524446 | 0.88 | GPR119 (0.40) | ALDH1A1MEN1KMT2AGAAGPR119 | |
| SCHEMBL4356877 | 0.88 | ALDH1A1 (0.45) | TSHRALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL4536702 | 0.88 | GPR119 (0.49) | GPR119 | |
| SCHEMBL4358687 | 0.87 | SMN1; SMN2 (0.46) | ALDH1A1MAPTKDM4ELMNACHRM2 | |
| SCHEMBL4354226 | 0.86 | KDM4E (0.45) | ALDH1A1MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |