SCHEMBL4357355

SCHEMBL4357355

C=Cc1cccc(C(=O)Oc2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.51
TDP1 Q9NUW8 3/20 0.51
MAPK1 P28482 2/20 0.50
NSD2 O96028 1/20 0.50
KMT2A Q03164 7/20 0.49
RAB9A P51151 1/20 0.49
ALDH1A1 P00352 3/20 0.48
TTR P02766 1/20 0.47
MEN1 O00255 2/20 0.47
PARP10 Q53GL7 1/20 0.46
KDM4E B2RXH2 2/20 0.46
ALOX5 P09917 1/20 0.45
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
GALR1 P47211 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PKM P14618 1/20 0.44
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5444107 0.90 KMT2A (0.54) MAPTTDP1NSD2KMT2ARAB9A
SCHEMBL17758430 0.85 UNG (0.61) MAPTTDP1MAPK1NSD2KMT2A
SCHEMBL69684 0.82 NSD2 (0.63) MAPTTDP1MAPK1NSD2KMT2A
SCHEMBL5942266 0.82 KMT2A (0.53) MAPTTDP1MAPK1KMT2AALDH1A1
SCHEMBL5200353 0.81 MAPT (0.57) MAPTTDP1NSD2KMT2ARAB9A
SCHEMBL1143616 0.81 KMT2A (0.66) MAPTTDP1KMT2ARAB9AALDH1A1
SCHEMBL28933415 0.81 MAPT (0.49) MAPTTDP1MAPK1NSD2KMT2A
SCHEMBL10946618 0.81 F2 (0.47) MAPTTDP1KMT2ARAB9AALDH1A1
SCHEMBL2904118 0.81 UNG (0.44) TDP1KMT2AALDH1A1TTRMEN1
SCHEMBL8673010 0.81 NSD2 (0.61) MAPTTDP1MAPK1NSD2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
US-20230004023-A1 DIFFRACTIVE CONTACT LENSES ALCON INC. (CH) 2023-01-05 US claimed
WO-2022263994-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-12-22 WO claimed
WO-2026105013-A1 CONTACT LENSES WITH COLOR FILTERING ZONE ALCON INC. (CH) 2026-05-21 WO disclosed
US-20260133439-A1 CONTACT LENSES WITH COLOR FILTERING ZONE ALCON INC. (CH) 2026-05-14 US disclosed
US-20260118700-A1 DIFFRACTIVE MULTIFOCAL CONTACT LENS ALCON INC (CH) 2026-04-30 US disclosed
US-20260104598-A1 COMPOSITE CONTACT LENSES WITH ULTRATHIN OBJECTS ALCON INC (CH) 2026-04-16 US disclosed
EP-4719750-A1 EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4719751-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4719753-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
CN-105593234-B Novel organopolysiloxane, the surface conditioning agent comprising it, the resin combination comprising it and their gel-like product or cured product 道康宁东丽株式会社 2018-10-26 CN disclosed
WO-2015023001-A1 NOVEL ORGANOPOLYSILOXANE, SURFACE TREATMENT AGENT COMPRISING THE SAME, RESIN COMPOSITION COMPRISING THE SAME, AND GELATINOUS PRODUCT OR CURED PRODUCT THEREOF DOW CORNING TORAY CO., LTD. (JP) 2015-02-19 WO disclosed
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
CN-100462389-C Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS INC (JP) 2009-02-18 CN disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
CN-1630676-A Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS INC (JP) 2005-06-22 CN disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260133439-A1 CONTACT LENSES WITH COLOR FILTERING ZONE MYO1G, STRA6, GJA1 MAPT 2948/4885TDP1 3729/4885MAPK1 51/4885
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA MAPT 2700/4885TDP1 2489/4885MAPK1 1718/4885
US-20260104598-A1 COMPOSITE CONTACT LENSES WITH ULTRATHIN OBJECTS CRYZ, CRYAA, LIMA1 MAPT 436/4885TDP1 3619/4885MAPK1 3808/4885
US-20260118700-A1 DIFFRACTIVE MULTIFOCAL CONTACT LENS DSG1, SDC1, DSP MAPT 2121/4885TDP1 3016/4885MAPK1 3005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.