SCHEMBL4359196

SCHEMBL4359196

CCOc1ccccc1OCCO

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 8/20 0.60
▸ MAPT P10636 4/20 0.60
▸ NPSR1 Q6W5P4 1/20 0.60
▸ TDP1 Q9NUW8 2/20 0.56
▸ CYP1A2 P05177 1/20 0.56
▸ CYP2D6 P10635 1/20 0.56
▸ CYP2C19 P33261 1/20 0.56
▸ GLA P06280 1/20 0.55
▸ ALDH1A1 P00352 6/20 0.52
▸ KDM4E B2RXH2 2/20 0.50
▸ GAA P10253 2/20 0.50
▸ RECQL P46063 1/20 0.50
▸ HTR1A P08908 1/20 0.50
▸ ADRA1D P25100 1/20 0.50
▸ ADRA1A P35348 1/20 0.50
▸ ADRA1B P35368 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ RAB9A P51151 1/20 0.49
▸ ATM Q13315 1/20 0.49
▸ HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL238824 0.89 ALDH1A1 (0.61) L3MBTL1MAPTNPSR1ALDH1A1KDM4E
SCHEMBL29510942 0.89 ALDH1A1 (0.61) L3MBTL1MAPTNPSR1ALDH1A1KDM4E
SCHEMBL13552184 0.87 ALDH1A1 (0.50) L3MBTL1MAPTNPSR1TDP1CYP1A2
SCHEMBL7821244 0.86 LMNA (0.62) L3MBTL1MAPTNPSR1TDP1CYP1A2
SCHEMBL4920959 0.86 L3MBTL1 (0.76) L3MBTL1MAPTNPSR1TDP1CYP1A2
SCHEMBL10337826 0.86 IDO1 (0.68) L3MBTL1MAPTNPSR1TDP1CYP1A2
SCHEMBL5391790 0.86 TSHR (0.49) L3MBTL1MAPTNPSR1TDP1CYP1A2
SCHEMBL10005200 0.86 L3MBTL1 (0.50) L3MBTL1MAPTNPSR1TDP1CYP1A2
SCHEMBL9440806 0.85 CYP1A2 (0.60) L3MBTL1MAPTNPSR1TDP1CYP1A2
1,2-Diethoxybenzene SCHEMBL578986 0.83 ALDH1A1 (0.68) L3MBTL1MAPTNPSR1TDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878508-A DC-Rhoin derivative, preparation method and application thereof 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) 2024-11-01 — — CN claimed
EP-1786764-B1 PROCESS FOR PREPARING TAMSULOSIN SCINOPHARM SINGAPORE PTE LTD (SG) 2017-03-15 — — EP claimed
US-7332621-B2 Process for preparing Tamsulosin SCINOPHARM TAIWAN KTD. (TW) 2008-02-19 — — US claimed
US-20070142669-A1 reacting o-ethoxyphenoxyethanol with sulfonyl chloride; reacting the sulfonate with (R)-(-)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide by condensation to produce Tamsulosin SCINOPHARM TAIWAN LTD. 2007-06-21 — — US claimed
EP-1786764-A2 PROCESS FOR PREPARING TAMSULOSIN Scinopharm Singapore Pte Ltd. (SG) 2007-05-23 — — EP claimed
WO-2006019358-A2 PROCESS FOR PREPARING TAMSULOSIN SCINOPHARM SINGAPORE PTE LTD. (SG) 2006-02-23 — — WO claimed
US-20060036113-A1 Process for preparing tamsulosin SCINOPHARM TAIWAN LTD. 2006-02-16 — — US claimed
US-12286418-B2 Compounds and methods for treating or preventing bacterial infections BAYLOR COLLEGE OF MEDICINE (US) 2025-04-29 — — US disclosed
CN-118878508-A DC-Rhoin derivative, preparation method and application thereof 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) 2024-11-01 — — CN disclosed
US-20220267303-A1 Compounds and Methods for Treating or Preventing Bacterial Infections BAYLOR COLLEGE OF MEDICINE 2022-08-25 — — US disclosed
WO-2022149081-A1 IMPROVED PROCESS FOR THE PREPARATION OF A COMPOUND USEFUL IN THE PREPARATION OF ANTI-ANDROGENIC COMPOUND OCIMUM LABS PRIVATE LIMITED (IN) 2022-07-14 — — WO disclosed
WO-2022149081-A1 IMPROVED PROCESS FOR THE PREPARATION OF A COMPOUND USEFUL IN THE PREPARATION OF ANTI-ANDROGENIC COMPOUND OCIMUM LABS PRIVATE LIMITED (IN) 2022-07-14 — — WO disclosed
WO-2020257734-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING, AMELIORATING, OR PREVENTING BACTERIAL INFECTIONS BAYLOR COLLEGE OF MEDICINE (US) 2020-12-24 — — WO disclosed
EP-1697316-A1 NOVEL INTERMEDIATES FOR THE SYNTHESIS OF (R)-TAMSULOSIN AND OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR THEIR PREPARATION PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE (FR) 2006-09-06 — — EP disclosed
WO-2006019358-A2 PROCESS FOR PREPARING TAMSULOSIN SCINOPHARM SINGAPORE PTE LTD. (SG) 2006-02-23 — — WO disclosed
WO-2006019358-A2 PROCESS FOR PREPARING TAMSULOSIN SCINOPHARM SINGAPORE PTE LTD. (SG) 2006-02-23 — — WO disclosed
CN-1736984-A Method for synthesizing tamsulosin medicine for resisting benign prostatic hyperplasia SHENLONG SINGAPORE PRIVATE CO (SG) 2006-02-22 — — CN disclosed
US-20060036113-A1 Process for preparing tamsulosin SCINOPHARM TAIWAN LTD. 2006-02-16 — — US disclosed
US-20060036113-A1 Process for preparing tamsulosin SCINOPHARM TAIWAN LTD. 2006-02-16 — — US disclosed
WO-2005058810-A1 NOVEL INTERMEDIATES FOR THE SYNTHESIS OF (R)-TAMSULOSIN AND OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR THEIR PREPARATION PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE (FR) 2005-06-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220267303-A1 Compounds and Methods for Treating or Preventing Bacterial Infections OXA1L, MMP8, OGG1 L3MBTL1 120/4885MAPT 4642/4885NPSR1 4123/4885
US-12286418-B2 Compounds and methods for treating or preventing bacterial infections OXA1L, MMP8, OGG1 L3MBTL1 120/4885MAPT 4642/4885NPSR1 4123/4885
US-20070142669-A1 reacting o-ethoxyphenoxyethanol with sulfonyl chloride; reacting the sulfonate with (R)-(-)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide by condensation to produce Tamsulosin BPHL, REN, MME L3MBTL1 4853/4885MAPT 3424/4885NPSR1 22/4885
US-20060036113-A1 Process for preparing tamsulosin BPHL, REN, TPSB2 L3MBTL1 4878/4885MAPT 2010/4885NPSR1 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback