Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | S100A9 | P06702 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810258 | 0.80 | ACLY (0.43) | MAPTPTGES2TP53DAOGAA | |
| SCHEMBL1811314 | 0.77 | TRPV4 (0.45) | MAPTGAACXCR2MCL1L3MBTL1 | |
| SCHEMBL3906458 | 0.75 | ACLY (0.47) | MCL1 | |
| SCHEMBL3917122 | 0.75 | NR1I2 (0.45) | DAOMCL1 | |
| SCHEMBL3917135 | 0.74 | PGR (0.48) | — | |
| SCHEMBL3908352 | 0.74 | MAPT (0.43) | MAPTTP53GAADRD2HTR2A | |
| SCHEMBL3911540 | 0.74 | DAO (0.40) | DAOCXCR2 | |
| SCHEMBL4352199 | 0.73 | BRPF1 (0.44) | DAO | |
| SCHEMBL1812628 | 0.73 | BRPF1 (0.41) | DAO | |
| SCHEMBL1818133 | 0.73 | PKM (0.43) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797042-B1 | INDOZOLONE DERIVATIVES AS 11B-HSD1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-01-07 | — | — | EP | claimed |