SCHEMBL4364337

SCHEMBL4364337

CCOC(C)c1nc(N)c2nc[nH]c2n1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 4/20 0.36
CCNB1 P14635 4/20 0.36
CCNA2 P20248 4/20 0.36
CDK2 P24941 4/20 0.36
CCNA1 P78396 4/20 0.36
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7165315 0.84 CDK1 (0.31) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL4241346 0.82 CYP3A4 (0.38) SMN1; SMN2
SCHEMBL6009519 0.80 ADORA2A (0.38) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL11801311 0.79 ADORA2A (0.31) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL67129 0.78 CDK1 (0.31) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL6267281 0.77 USP2 (0.30) SMN1; SMN2
SCHEMBL4364347 0.77 CDK1 (0.49) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL6692346 0.75 BTK (0.31)
SCHEMBL19539317 0.74 ADORA2A (0.36) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL8207458 0.73 CDK1 (0.40) CDK1CCNB1CCNA2CDK2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210219546-A1 METHODS OF TREATING CROP PLANTS ALTER DOMUS US LLC 2021-07-22 US disclosed
EP-3294052-A1 METHODS OF TREATING CROP PLANTS Agrofresh, Inc. (US) 2018-03-21 EP disclosed
WO-2016182995-A1 METHODS OF TREATING CROP PLANTS AGROFRESH INC (US) 2016-11-17 WO disclosed
US-20150282479-A1 METHODS OF TREATING CROP PLANTS AGROFRESH, INC. 2015-10-08 US disclosed
US-9055741-B2 Contacting crop plants with compositions ROHM AND HAAS COMPANY (US) 2015-06-16 US disclosed
EP-1856976-B1 Contacting crop plants with compositions ROHM & HAAS (US) 2014-09-03 EP disclosed
EP-2070419-A1 A liquid composition for treating plants Rohm and Haas Company (US) 2009-06-17 EP disclosed
EP-1856976-A2 Contacting crop plants with compositions Rohm and Haas Company (US) 2007-11-21 EP disclosed
US-20070265166-A1 Contacting crop plants with compositions ALTER DOMUS US LLC 2007-11-15 US disclosed
US-20070117720-A1 Compositions with cyclopropenes AGROFRESH, INC. 2007-05-24 US disclosed
EP-1787513-A2 Compositions with cyclopropenes Rohm and Haas Company (US) 2007-05-23 EP disclosed
US-20060160704-A1 Plant growth regulation BASEL RICHARD M 2006-07-20 US disclosed
EP-1680960-A1 Plant growth regulation Rohm and Haas Company (US) 2006-07-19 EP disclosed
WO-1998011121-A1 BIOLOGICALLY ACTIVE PHOSPHOTRIESTER-TYPE COMPOUNDS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1998-03-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070265166-A1 Contacting crop plants with compositions PIN1, MYB, CROCC CDK1 2297/4885CCNB1 1409/4885CCNA2 1917/4885
US-20060160704-A1 Plant growth regulation MYB, SLTM, YAP1 CDK1 4000/4885CCNB1 2236/4885CCNA2 2303/4885
US-20150282479-A1 METHODS OF TREATING CROP PLANTS CYCS, NOP2, CNPY3 CDK1 2143/4885CCNB1 1190/4885CCNA2 2916/4885
US-20070117720-A1 Compositions with cyclopropenes MYB, OSBP, FAR1 CDK1 3432/4885CCNB1 571/4885CCNA2 416/4885
US-20210219546-A1 METHODS OF TREATING CROP PLANTS CYCS, NOP2, CNPY3 CDK1 2143/4885CCNB1 1190/4885CCNA2 2916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.