Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436945 | 0.87 | KDM4E (0.45) | ALDH1A1KDM4EKMT2APOLBRAD52 | |
| SCHEMBL436601 | 0.84 | KMT2A (0.33) | ALDH1A1KDM4EKMT2APOLBRAD52 | |
| SCHEMBL437542 | 0.84 | KDM4E (0.33) | ALDH1A1KDM4EKMT2APOLBRAD52 | |
| SCHEMBL439044 | 0.79 | HAVCR2 (0.47) | ALDH1A1KDM4EKMT2AHTTHPGD | |
| SCHEMBL435828 | 0.76 | ACHE (0.39) | ALDH1A1KDM4EKMT2APOLBRAD52 | |
| SCHEMBL438293 | 0.74 | NPC1 (0.55) | ALDH1A1KDM4EKMT2ASMN1; SMN2MAPT | |
| SCHEMBL441685 | 0.74 | ACHE (0.35) | ALDH1A1KDM4EKMT2APOLBRAD52 | |
| SCHEMBL442244 | 0.73 | ACHE (0.43) | ALDH1A1KDM4EKMT2APOLBRAD52 | |
| SCHEMBL439148 | 0.73 | NR4A2 (0.40) | ALDH1A1KDM4EKMT2ASMN1; SMN2HTT | |
| SCHEMBL31328707 | 0.70 | GAA (0.32) | KMT2AHTTMAPTACHEGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |