Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438361 | 0.87 | ALDH1A1 (0.36) | KDM4EALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL435828 | 0.86 | ACHE (0.39) | KDM4EALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL441685 | 0.83 | ACHE (0.35) | KDM4EALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL436601 | 0.83 | KMT2A (0.33) | KDM4EALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL437457 | 0.79 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL441701 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL437086 | 0.73 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL437542 | 0.72 | KDM4E (0.33) | KDM4EALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL442244 | 0.71 | ACHE (0.43) | KDM4EALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL437599 | 0.71 | CCR1 (0.42) | KDM4EALDH1A1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |