Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436520 | 0.82 | CYP2D6 (0.41) | MCHR1KCNH2 | |
| SCHEMBL437914 | 0.81 | CTSS (0.41) | CTSKCTSSMCHR1 | |
| SCHEMBL439825 | 0.79 | NR4A2 (0.60) | MCHR1ACHE | |
| SCHEMBL440380 | 0.79 | ALDH1A1 (0.49) | CTSKCTSSMCHR1EIF4A1 | |
| SCHEMBL30604783 | 0.77 | KCNH2 (0.46) | KCNH2ESR1 | |
| SCHEMBL30604781 | 0.77 | KCNH2 (0.46) | KCNH2ESR1 | |
| SCHEMBL438754 | 0.77 | HSP90AB1 (0.52) | MCHR1 | |
| SCHEMBL31690948 | 0.76 | NR4A2 (0.47) | ACHEKCNH2ESR1 | |
| SCHEMBL436015 | 0.74 | NOS3 (0.39) | CTSKCTSSMCHR1 | |
| SCHEMBL441586 | 0.72 | KDM4E (0.60) | MCHR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |