Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 15/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436520 | 0.82 | CYP2D6 (0.41) | NOS3NOS1NOS2SMN1; SMN2MCHR1 | |
| SCHEMBL438849 | 0.78 | NOS3 (0.41) | NOS3NOS1NOS2NPC1TP53 | |
| SCHEMBL438225 | 0.76 | MCHR1 (0.42) | NOS3NOS1NOS2MCHR1ASIC3 | |
| SCHEMBL441540 | 0.76 | NR4A2 (0.51) | HSD17B10 | |
| SCHEMBL439885 | 0.75 | NOS3 (0.41) | NOS3NOS1NOS2NPC1MCHR1 | |
| SCHEMBL440069 | 0.75 | NOS2 (0.41) | NOS3NOS1NOS2MCHR1ASIC3 | |
| SCHEMBL439432 | 0.74 | MCHR1 (0.49) | NOS3NOS1NOS2MCHR1ASIC3 | |
| SCHEMBL436808 | 0.74 | CTSK (0.45) | MCHR1CTSSCTSK | |
| SCHEMBL440380 | 0.73 | ALDH1A1 (0.49) | NOS3NOS1NOS2MCHR1BACE1 | |
| SCHEMBL439825 | 0.73 | NR4A2 (0.60) | NOS3NOS1NOS2MCHR1ASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |