Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437914 | 0.84 | CTSS (0.41) | HSP90AB1MCHR1PDE10A | |
| SCHEMBL13409411 | 0.81 | HSP90AB1 (0.44) | HSP90AB1KDM4EPDE10ASREBF2ALDH1A1 | |
| SCHEMBL440380 | 0.79 | ALDH1A1 (0.49) | KDM4EMCHR1ALDH1A1HPGDTDP1 | |
| SCHEMBL436520 | 0.79 | CYP2D6 (0.41) | KDM4EMCHR1SMN1; SMN2TDP1 | |
| SCHEMBL439825 | 0.79 | NR4A2 (0.60) | HSP90AB1KDM4EMCHR1PARP1 | |
| SCHEMBL441787 | 0.79 | MCHR1 (0.37) | HSP90AB1MCHR1 | |
| SCHEMBL437287 | 0.77 | NR4A2 (0.61) | KDM4EMCHR1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL436808 | 0.77 | CTSK (0.45) | MCHR1 | |
| SCHEMBL18682211 | 0.74 | PDE10A (0.68) | MCHR1PDE10A | |
| SCHEMBL23473307 | 0.72 | KDM4E (0.51) | HSP90AB1KDM4EPDE10AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |