Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18616343 | 0.84 | LMNA (0.39) | LMNATP53SLC5A2PDK2MAOA | |
| SCHEMBL4363601 | 0.82 | PKM (0.50) | LMNATP53MAPTHPGDMEN1 | |
| SCHEMBL25460977 | 0.81 | PDE4A (0.46) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21208423 | 0.81 | PRKCE (0.35) | LMNATP53MAPTSLC5A2PDK2 | |
| SCHEMBL148755 | 0.81 | SHBG (0.48) | SHBGMAPTHPGDRECQLVDR | |
| SCHEMBL29741490 | 0.81 | SHBG (0.48) | SHBGMAPTHPGDRECQLVDR | |
| SCHEMBL4372632 | 0.79 | MAPT (0.40) | SHBGLMNATP53MAPTPDE4A | |
| SCHEMBL8750643 | 0.79 | NPC1 (0.42) | LMNATP53MAPTPDK2MAOA | |
| SCHEMBL4380347 | 0.78 | SHBG (0.44) | SHBGLMNATP53MAPTPDE4A | |
| SCHEMBL4677534 | 0.78 | TSHR (0.43) | LMNATP53MAPTPDK2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107886-A1 | Lignin Oxidation and Products Thereof | STRATEGIC ENZYME APPLICATIONS, INC. (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107886-A1 | Lignin Oxidation and Products Thereof | LOX, LPO, NOX4 | SHBG 2868/4885LMNA 566/4885TP53 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.