Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.32 |
| ▸ | MYLK | Q15746 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372632 | 0.90 | MAPT (0.40) | SHBGMAPTPDE4APDE4BPDE4C | |
| SCHEMBL1229317 | 0.81 | SHBG (0.42) | SHBGMAPTPDE4APDE4BPDE4C | |
| SCHEMBL15957652 | 0.81 | SHBG (0.52) | SHBGMAPTPDE4APDE4BPDE4C | |
| SCHEMBL4570823 | 0.81 | HPGD (0.36) | MAPTHPGDHSD17B10PRKCEMYLK | |
| SCHEMBL1229578 | 0.79 | SHBG (0.40) | SHBGMAPTPDE4APDE4BPDE4C | |
| SCHEMBL14432651 | 0.79 | SHBG (0.47) | SHBGMAPTHPGDHSD17B10PRKCE | |
| SCHEMBL4371091 | 0.78 | SHBG (0.41) | SHBGMAPTPDE4APDE4BPDE4C | |
| SCHEMBL13384685 | 0.76 | CYP3A4 (0.45) | MAPTHPGDHSD17B10PRKCEMYLK | |
| SCHEMBL16854091 | 0.76 | SHBG (0.52) | SHBGMAPTHPGDHSD17B10PRKCE | |
| SCHEMBL16597205 | 0.74 | ALDH1A1 (0.39) | MAPTHPGDHSD17B10PRKCEMYLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107886-A1 | Lignin Oxidation and Products Thereof | STRATEGIC ENZYME APPLICATIONS, INC. (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107886-A1 | Lignin Oxidation and Products Thereof | LOX, LPO, NOX4 | SHBG 2868/4885MAPT 2282/4885PDE4A 3111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.