Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440440 | 0.81 | HAVCR2 (0.47) | GABRA1GABRB2HAVCR2KMT2ARAB9A | |
| SCHEMBL442133 | 0.79 | BACE1 (0.41) | HAVCR2KMT2ACTSBMEN1APAF1 | |
| SCHEMBL441701 | 0.78 | ALDH1A1 (0.43) | HAVCR2KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL442207 | 0.77 | HAVCR2 (0.65) | GABRA1GABRB2HAVCR2KMT2ARAB9A | |
| SCHEMBL441951 | 0.75 | HAVCR2 (0.58) | GABRA1GABRB2HAVCR2KMT2AGABRG2 | |
| SCHEMBL435823 | 0.75 | PARP1 (0.41) | HAVCR2KMT2ACTSBALOX5APFEN1 | |
| SCHEMBL22492368 | 0.75 | GABRA1 (0.45) | GABRA1GABRB2KMT2ARAB9ANPC1 | |
| SCHEMBL435849 | 0.74 | HTR1A (0.44) | — | |
| SCHEMBL440370 | 0.74 | PARP1 (0.45) | PARP1 | |
| SCHEMBL440812 | 0.73 | KMT2A (0.70) | HAVCR2KMT2ARAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |