Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437767 | 0.83 | HAVCR2 (0.46) | BACE1HAVCR2MEN1APAF1TDP2 | |
| SCHEMBL435823 | 0.83 | PARP1 (0.41) | HAVCR2MEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL441951 | 0.83 | HAVCR2 (0.58) | HAVCR2MEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL441701 | 0.83 | ALDH1A1 (0.43) | HAVCR2MEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL440370 | 0.79 | PARP1 (0.45) | CDK5AXLGSK3BDYRK1A | |
| SCHEMBL435849 | 0.79 | HTR1A (0.44) | EGFR | |
| SCHEMBL437613 | 0.79 | GABRA1 (0.41) | HAVCR2MEN1APAF1TDP2ALDH1A1 | |
| SCHEMBL28310895 | 0.78 | HAVCR2 (0.52) | HAVCR2KMT2A | |
| SCHEMBL437026 | 0.78 | HAVCR2 (0.68) | HAVCR2KMT2ANR4A2 | |
| SCHEMBL28310894 | 0.76 | PABPC1 (0.36) | BACE1HAVCR2MEN1APAF1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |