Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 5/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.34 |
| ▸ | GOT1 | P17174 | 1/20 | 0.34 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.34 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5835687 | 0.76 | HTR2C (0.40) | HTR2CHTR2ANOTUMMEN1KMT2A | |
| SCHEMBL14382060 | 0.68 | HTR2C (0.41) | HTR2CHTR2ANOTUMMEN1KMT2A | |
| SCHEMBL3467602 | 0.66 | NOTUM (0.39) | HTR2CHTR2ANOTUMMEN1KMT2A | |
| SCHEMBL437839 | 0.66 | HTR2C (0.38) | HTR2CHTR2ANOTUMMEN1KMT2A | |
| SCHEMBL1365863 | 0.64 | HTR2C (0.41) | HTR2CHTR2ANOTUMMEN1KMT2A | |
| SCHEMBL11179442 | 0.63 | HTR2C (0.42) | HTR2CHTR2ANOTUMMEN1KMT2A | |
| SCHEMBL13246537 | 0.62 | CTSD (0.42) | HTR2CHTR2ANOTUMMEN1KMT2A | |
| SCHEMBL28509266 | 0.61 | NOTUM (0.42) | HTR2CHTR2ANOTUMHTR2BADRA2A | |
| SCHEMBL1520975 | 0.61 | HTR2C (0.51) | HTR2CHTR2ANOTUMMEN1KMT2A | |
| SCHEMBL3050637 | 0.61 | SRD5A1 (0.36) | HTR2CHTR2ANOTUMHTR2BADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107923-B1 | WATER-SOLUBLE O-CARBONYL PHOSPHORAMIDATE PRODRUGS FOR THERAPEUTIC ADMINISTRATION | SHANGHAI MICURX PHARMACEUTICAL CO LTD (CN) | 2021-11-03 | — | — | EP | disclosed |
| EP-2185549-B1 | ANTIMICROBIAL ORTHO-FLUOROPHENYL OXAZOLIDINONES FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS INC (KY) | 2018-10-03 | — | — | EP | disclosed |
| US-9382276-B2 | Water-soluble O-carbonyl phosphoramidate prodrugs for therapeutic administration | MICURX PHARMACEUTICALS, INC. (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150239922-A1 | WATER-SOLUBLE O-CARBONYL PHOSPHORAMIDATE PRODRUGS FOR THERAPEUTIC ADMINISTRATION | SHANGHAI MICURX PHARMACEUTICAL CO. LTD. (CN) | 2015-08-27 | — | — | US | disclosed |
| US-20120190713-A1 | ANTIMICROBIAL ORTHO-FLUOROPHENYL OXAZOLIDINONES FOR TREATMENT OF BACTERIAL INFECTIONS | GORDEEV MIKHAIL FEDOROVICH (US) | 2012-07-26 | — | — | US | disclosed |
| US-8178683-B2 | Antimicrobial ortho-fluorophenyl oxazolidinones for treatment of bacterial infections | MICURX PHARMACEUTICALS, INC. (KY) | 2012-05-15 | — | — | US | disclosed |
| US-20120065170-A1 | Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | US | disclosed |
| US-20100204477-A1 | Methods and Processes For Syntheses and Manufacture of Antimicrobial 1(Ortho-Fluorophenyl)dihydropyridones | MICURX PHARMACEUTICALS, INC. (KY) | 2010-08-12 | — | — | US | disclosed |
| WO-2010091272-A1 | METHODS AND PROCESSES FOR SYNTHESES AND MANUFACTURE OF ANTIMICROBIAL 1-(ORTHO-FLUOROPHENYL)DIHYDROPYRIDONES | MICURX PHARMACEUTICALS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |
| WO-2010047737-A2 | ANTIMICROBIAL INDOLINE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (KY) | 2010-04-29 | — | — | WO | disclosed |
| US-20100069441-A1 | ANTIMICROBIAL INDOLINE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | GORDEEV MIKHAIL FEDOROVICH | 2010-03-18 | — | — | US | disclosed |
| US-20090048305-A1 | Antimicrobial ortho-Fluorophenyl Oxazolidinones For Treatment of Bacterial Infections | SHANGHAI MICURX PHARMACEUTICAL CO. LTD. (CN) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190713-A1 | ANTIMICROBIAL ORTHO-FLUOROPHENYL OXAZOLIDINONES FOR TREATMENT OF BACTERIAL INFECTIONS | OXA1L, OGFOD1, OLA1 | HTR2C 4696/4885HTR2A 4794/4885NOTUM 3133/4885 |
| US-20100204477-A1 | Methods and Processes For Syntheses and Manufacture of Antimicrobial 1(Ortho-Fluorophenyl)dihydropyridones | DHPS, FDPS, CYP2F1 | HTR2C 4361/4885HTR2A 4486/4885NOTUM 2780/4885 |
| US-20100069441-A1 | ANTIMICROBIAL INDOLINE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | IDO1, IDO2, INMT | HTR2C 89/4885HTR2A 139/4885NOTUM 3300/4885 |
| US-20150239922-A1 | WATER-SOLUBLE O-CARBONYL PHOSPHORAMIDATE PRODRUGS FOR THERAPEUTIC ADMINISTRATION | DPYD, SI, NUDT1 | HTR2C 4735/4885HTR2A 4804/4885NOTUM 2210/4885 |
| US-20090048305-A1 | Antimicrobial ortho-Fluorophenyl Oxazolidinones For Treatment of Bacterial Infections | OXA1L, OGFOD1, OLA1 | HTR2C 4696/4885HTR2A 4794/4885NOTUM 3133/4885 |
| US-20120065170-A1 | Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections | NISCH, SI, VIP | HTR2C 963/4885HTR2A 2225/4885NOTUM 2894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.