Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | KMT5B | Q4FZB7 | 1/20 | 0.31 |
| ▸ | KMT5C | Q86Y97 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.31 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436602 | 0.82 | ACHE (0.44) | ACHEMAPK13CDK1PIM1DYRK1A | |
| SCHEMBL437551 | 0.78 | NR4A2 (0.51) | ACHEEGFRNR4A2SOS2 | |
| SCHEMBL437126 | 0.77 | NOS3 (0.38) | HTTKMT2A | |
| SCHEMBL437195 | 0.76 | UHRF1 (0.35) | HTTKMT2AEGFR | |
| SCHEMBL437952 | 0.73 | ACHE (0.45) | ACHEHTTKMT2A | |
| SCHEMBL438613 | 0.73 | BCHE (0.45) | ACHEHTTPIM1PIM3 | |
| SCHEMBL21358444 | 0.73 | PDPK1 (0.47) | ACHEEGFR | |
| SCHEMBL437503 | 0.72 | TNF (0.35) | ACHE | |
| SCHEMBL438876 | 0.70 | BCHE (0.43) | ACHEHTTKMT2ACA1CA2 | |
| SCHEMBL439853 | 0.70 | BCHE (0.43) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |