Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437834 | 0.86 | SLC2A1 (0.45) | TAAR1SLC2A1PTGS1PTGS2 | |
| SCHEMBL435782 | 0.82 | SLC2A1 (0.38) | KDM4ETAAR1SMN1; SMN2SLC2A1KMT2A | |
| SCHEMBL439409 | 0.79 | LRRK2 (0.55) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL439183 | 0.79 | HTR6 (0.41) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL440242 | 0.78 | LRRK2 (0.54) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL438559 | 0.77 | BRD4 (0.36) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL437304 | 0.75 | PTGS1 (0.39) | ALKBH3SMN1; SMN2SLC2A1PTGS1PTGS2 | |
| SCHEMBL9370750 | 0.75 | OPRM1 (0.40) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL439027 | 0.74 | UTS2R (0.54) | KDM4EUTS2RALKBH3GAAMEN1 | |
| SCHEMBL437141 | 0.74 | SMN1; SMN2 (0.51) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513277-B2 | Pyrrolo[3,2-C] pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2013-08-20 | — | — | US | disclosed |
| US-8148529-B2 | Pyrrolo[3,2-C] pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2012-04-03 | — | — | US | disclosed |
| US-20120065224-A1 | PYRROLO[3,2-C) PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2012-03-15 | — | — | US | disclosed |
| EP-1784402-B1 | PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-08-03 | — | — | EP | disclosed |
| US-20090005409-A1 | Pyrrolo[3,2-C] Pyrdine Derivatives and Processes for the Preparation Thereof | YUHAN CORPORATION (KR) | 2009-01-01 | — | — | US | disclosed |
| EP-1784402-A1 | PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2007001139-A1 | A COMPOSITION FOR TREATING OR PREVENTING A CANCER COMPRISING PYRROLOPYRIDINE DERIVATIVES | YUHAN CORPORATION (KR) | 2007-01-04 | — | — | WO | disclosed |
| WO-2006025714-A1 | PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005409-A1 | Pyrrolo[3,2-C] Pyrdine Derivatives and Processes for the Preparation Thereof | ATP6AP1, PPOX, PGA5 | CCNB2 3383/4885CDK1 2479/4885CCNB1 3883/4885 |
| US-20120065224-A1 | PYRROLO[3,2-C) PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | PGA5, ATP6AP1, HPD | CCNB2 3764/4885CDK1 2090/4885CCNB1 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.