Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Vanillyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vanillyl Alcohol SCHEMBL4396135 | 0.95 | CYP1A2 (0.50) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| Vanillyl Alcohol SCHEMBL117979 | 0.94 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| Vanillyl Alcohol SCHEMBL3386819 | 0.92 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| Vanillyl Alcohol SCHEMBL15272606 | 0.92 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| Vanillyl Alcohol SCHEMBL14358230 | 0.92 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| Vanillyl Alcohol SCHEMBL117402 | 0.88 | CYP3A4 (0.52) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL18454017 | 0.83 | HTR1A (0.64) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL15272605 | 0.83 | EPHX2 (0.52) | — | |
| Vanillyl Alcohol SCHEMBL117923 | 0.82 | TAAR1 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| Alcohol SCHEMBL579289 | 0.82 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11160734-B2 | Personal care compositions comprising shaped abrasive particles | THE PROCTER & GAMBLE COMPANY (US) | 2021-11-02 | — | — | US | disclosed |
| EP-2720666-B1 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | PROCTER & GAMBLE (US) | 2019-03-20 | — | — | EP | disclosed |
| US-20170312190-A1 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | PROCTER & GAMBLE (US) | 2017-11-02 | — | — | US | disclosed |
| US-9675531-B2 | Personal care compositions comprising shaped abrasive particles | THE PROCTER & GAMBLE COMPANY (US) | 2017-06-13 | — | — | US | disclosed |
| US-20160367091-A9 | Personal Care Compositions Comprising a Di-Amido Gellant and Methods of Using | THE PROCTER & GAMBLE COMPANY | 2016-12-22 | — | — | US | disclosed |
| US-9271912-B2 | Personal care compositions comprising a pH tuneable gellant and methods of using | THE PROCTER & GAMBLE COMPANY (US) | 2016-03-01 | — | — | US | disclosed |
| EP-2720666-A2 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | The Procter and Gamble Company (US) | 2014-04-23 | — | — | EP | disclosed |
| EP-2717967-A2 | PERSONAL CARE COMPOSITIONS COMPRISING A pH TUNEABLE GELLANT AND METHODS OF USING | The Procter & Gamble Company (US) | 2014-04-16 | — | — | EP | disclosed |
| US-20130336902-A1 | Personal Care Compositions Comprising a Di-Amido Gellant and Methods of Using | FERNANDEZ PRIETO SUSANA (ES) | 2013-12-19 | — | — | US | disclosed |
| US-20130336903-A1 | Personal Care Compositions Comprising a pH Tuneable Gellant and Methods of Using | THE PROCTER & GAMBLE COMPANY | 2013-12-19 | — | — | US | disclosed |
| US-20130039961-A1 | Personal Care Compositions Comprising Shaped Abrasive Particles | THE PROCTER & GAMBLE COMPANY | 2013-02-14 | — | — | US | disclosed |
| WO-2012177757-A2 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | THE PROCTER & GAMBLE COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012174091-A2 | PERSONAL CARE COMPOSITIONS COMPRISING A pH TUNEABLE GELLANT AND METHODS OF USING | THE PROCTER & GAMBLE COMPANY (US) | 2012-12-20 | — | — | WO | disclosed |
| EP-2120843-A1 | PERSONAL CARE KIT HAVING SKIN CARE COMPOSITIONS WITH A READILY PERCEPTIBLE DIFFERENCE | The Procter and Gamble Company (US) | 2009-11-25 | — | — | EP | disclosed |
| US-20090017080-A1 | PERSONAL CARE KIT HAVING SKIN CARE COMPOSITIONS WITH A READILY PERCEPTIBLE DIFFERENCE | THE PROCTER & GAMBLE COMPANY | 2009-01-15 | — | — | US | disclosed |
| WO-2008112964-A1 | PERSONAL CARE KIT HAVING SKIN CARE COMPOSITIONS WITH A READILY PERCEPTIBLE DIFFERENCE | THE PROCTER & GAMBLE COMPANY (US) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170312190-A1 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | POLR1C, PLOD3, C9 | CYP1A2 3521/4885CYP3A4 4459/4885CYP2C9 2414/4885 |
| US-11160734-B2 | Personal care compositions comprising shaped abrasive particles | POLR1C, PLOD3, C9 | CYP1A2 3521/4885CYP3A4 4459/4885CYP2C9 2414/4885 |
| US-20130336903-A1 | Personal Care Compositions Comprising a pH Tuneable Gellant and Methods of Using | ARGLU1, F12, GALR1 | CYP1A2 3571/4885CYP3A4 4250/4885CYP2C9 2256/4885 |
| US-20130336902-A1 | Personal Care Compositions Comprising a Di-Amido Gellant and Methods of Using | PARN, PARG, CUTA | CYP1A2 3788/4885CYP3A4 4491/4885CYP2C9 2084/4885 |
| US-20130039961-A1 | Personal Care Compositions Comprising Shaped Abrasive Particles | POLR1C, PLOD3, C9 | CYP1A2 3521/4885CYP3A4 4459/4885CYP2C9 2414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.