Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438820 | 0.83 | HAVCR2 (0.39) | HAVCR2LMNAPOLBMAPTMEN1 | |
| SCHEMBL440009 | 0.83 | HAVCR2 (0.38) | HAVCR2MAPTMEN1GAAKMT2A | |
| SCHEMBL441951 | 0.79 | HAVCR2 (0.58) | HAVCR2LMNAMAPTMEN1KMT2A | |
| SCHEMBL439672 | 0.74 | DYRK1A (0.35) | HAVCR2SMN1; SMN2 | |
| SCHEMBL439785 | 0.73 | HAVCR2 (0.68) | HAVCR2LMNAPOLBMAPTMEN1 | |
| SCHEMBL439739 | 0.73 | CCR1 (0.39) | HAVCR2MAPTMEN1NPC1RAB9A | |
| SCHEMBL442133 | 0.72 | BACE1 (0.41) | HAVCR2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL437507 | 0.71 | MAP4K4 (0.35) | — | |
| SCHEMBL437599 | 0.71 | CCR1 (0.42) | HAVCR2LMNAPOLBMAPTMEN1 | |
| SCHEMBL438876 | 0.71 | BCHE (0.43) | HAVCR2MAPTKMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |