Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418449 | 0.85 | MTNR1A (0.55) | ADRB2PLA2G2AAKR1C3AKR1C2MTNR1A | |
| SCHEMBL4393646 | 0.80 | TAAR1 (0.47) | PLA2G2AMTNR1AMTNR1BLMNATSHR | |
| SCHEMBL4397542 | 0.75 | MTNR1A (0.40) | MTNR1ANQO2MTNR1BLMNACYP1A2 | |
| SCHEMBL1971963 | 0.74 | MTNR1A (0.72) | ADRB2AKR1C3AKR1C2MTNR1APTGS1 | |
| SCHEMBL17369615 | 0.72 | PTGS1 (0.82) | AKR1C3AKR1C2PTGS1LMNACYP1A2 | |
| SCHEMBL10876035 | 0.72 | AKR1C3 (0.76) | PLA2G2AAKR1C3AKR1C2PTGS1LMNA | |
| SCHEMBL4385656 | 0.72 | CA2 (0.35) | CYP1A2TSHR | |
| SCHEMBL8688610 | 0.71 | MTNR1A (0.75) | MTNR1ANQO2MTNR1BCYP1A2CYP2D6 | |
| SCHEMBL2701682 | 0.70 | ADRB2 (0.56) | ADRB2PLA2G2AMTNR1APTGS1NQO2 | |
| SCHEMBL2403262 | 0.69 | HTR1D (0.65) | AKR1C2MTNR1ANQO2MTNR1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005430-A1 | Receptor Blocker and Vasodilator Comprising Indole Derivative as Active Ingredient | NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005430-A1 | Receptor Blocker and Vasodilator Comprising Indole Derivative as Active Ingredient | ADRB2, ADRB1, ADRA2B | ADRB2 1/4885PLA2G2A 1497/4885AKR1C3 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.